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急性肺损伤与急性呼吸窘迫综合征中肺泡壁通透性与肺泡上皮损伤血清学标志物的研究进展 被引量：4

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摘要 急性肺损伤／急性呼吸窘迫综合征（ALI／ARDS）是累及呼吸系统的危重症，病死率高达38．5％。目前临床诊断ALI／ARDS主要依赖氧合指数和肺部影像学改变，而上述改变往往在肺部病变严重且呼吸功能严重受损后才出现，具有滞后性，因此需要更敏感的指标辅助预测ALI／ARDS的发生、判断病变程度及评估预后。
作者 吴晓东 苏欣 朱美英 施毅
机构地区 南京大学医学院临床学院（南京军区南京总医院）呼吸科
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2011年第11期846-849,共4页 Chinese Journal of Tuberculosis and Respiratory Diseases
基金 南京军区医药卫生重点课题（092028） 江苏省自然科学基金（BK2009318） 中国博士后科学基金（20100471844）
关键词 急性呼吸窘迫综合征 急性肺损伤 血清学标志物 上皮损伤 肺泡壁 ALI/ARDS 通透性 肺部病变
分类号 R563.8 [医药卫生—呼吸系统]
作者简介 通信作者：施毅，Email：shiyi56@126．com
  • 相关文献

参考文献37

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二级参考文献13

  • 1詹庆元,王辰.肺泡复张手法治疗急性呼吸窘迫综合征[J].国外医学（呼吸系统分册）,2005,25(7):520-523. 被引量：7
  • 2舒林华,吴秀清,魏克伦,舒林宏,薛辛东,吴红敏,宗志宏,高红.肺表面活性物质蛋白-D在脂多糖诱导的急性肺损伤幼鼠中的时序变化(英文)[J].中国当代儿科杂志,2005,7(6):483-488. 被引量：17
  • 3急性肺损伤/急性呼吸窘迫综合征诊断与治疗指南(2006)[J].中华内科杂志,2007,46(5):430-435. 被引量：241
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共引文献18

同被引文献47

  • 1张小妮,金敏,陈超.机械通气新生儿血浆肺表面活性物质蛋白A和血清铁蛋白的变化[J].实用儿科临床杂志,2007,22(2):115-116. 被引量：3
  • 2雷联会,俞森洋,韦中余,王瑜贵,杨洋.原位肝移植术后早期发生急性肺损伤危险因素的多元Logistic回归分析[J].中国呼吸与危重监护杂志,2007,6(3):194-196. 被引量：9
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  • 5Matthay MA, Zemans RL. The acute respiratory distress syndrome: pathogenesis and treatment. Annu Rev Pathol, 2011,6 : 147-163.
  • 6Diaz JV, Brower R, Calfee CS, et al. Therapeutic strategies for severe acute lung injury. Crit Care Med, 2010, 38: 1644- 1650.
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引证文献4

二级引证文献23

中华结核和呼吸杂志
2011年 第11期

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