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SREBPs信号转导途径与动脉粥样硬化研究进展 被引量：3

Insights into Sterol Regulatory Element Binding Protein in Atherosclerosis
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摘要 固醇调节元件结合蛋白对细胞内胆固醇的稳态调节有重要作用,近几年研究发现固醇调节元件结合蛋白广泛参与了动脉粥样硬化危险因素如吸烟、高血糖、脂代谢障碍、肥胖、高血压等的促动脉粥样硬化作用,现就固醇调节元件结合蛋白在动脉粥样硬化中作用的最新进展做一综述,有助于对动脉粥样硬化的发病机理有更新、更全面的认识。 Sterol regulatory element binding proteins（SREBPs） are key regulators of cellular lipid homeostasis.In recent years research has shown that SREBPs are involved in atherosclerosis risk factors such as smoking,diabetes,lipid metabolism disorders,obesity,hypertension,and others.This review addresses the role of the SREBPs in atherosclerosis in order to provide fresh insights into atherosclerosis.
作者 李博 李卫华
机构地区 厦门大学附属第一医院心血管内科
出处 《心血管病学进展》 CAS 2011年第6期876-879,共4页 Advances in Cardiovascular Diseases
关键词 动脉粥样硬化 固醇调节元件结合蛋白 胆固醇 atherosclerosis sterol regulatory element binding proteins cholesterol
分类号 R543.5 [医药卫生—心血管疾病]
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共引文献97

同被引文献58

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心血管病学进展
2011年 第6期

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