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The Role of Dorsal Raphe Nucleus and 5-HT in the Electro-acupunctural Inhibition of the cAMP Induced ECoG Epileptiform Activities in Rabbits

The Role of Dorsal Raphe Nucleus and 5-HT in the Electro-acupunctural Inhibition of the cAMP Induced ECoG Epileptiform Activities in Rabbits
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摘要 Like electroacupuncture (EA),electrical stimulation of the dorsal raphe nucle-us (DRN)also inhibits the cAMP induced cortical epileptic waves and the EA inducedinhibition can be abolished or markedly reduced by iv cyproheptadine (CYP) or destruc-tion of DRN by electrolysis.The results suggest that 5-HT neurons in the DRN mayplay an important role in the EA inhibition of the generation of cAMP induced elec-trocorticogram (ECoG) epileptic waves. Like electroacupuncture (EA),electrical stimulation of the dorsal raphe nucle- us (DRN)also inhibits the cAMP induced cortical epileptic waves and the EA induced inhibition can be abolished or markedly reduced by iv cyproheptadine (CYP) or destruc- tion of DRN by electrolysis.The results suggest that 5-HT neurons in the DRN may play an important role in the EA inhibition of the generation of cAMP induced elec- trocorticogram (ECoG) epileptic waves.
出处 《Journal of Medical Colleges of PLA(China)》 CAS 1990年第2期151-156,共6页 中国人民解放军军医大学学报(英文版)
关键词 epileptic waves ELECTROCORTICOGRAM CAMP electroacupuncture dorsal RAPHE nucleus CYPROHEPTADINE epileptic waves electrocorticogram cAMP electroacupuncture dorsal raphe nucleus cyproheptadine
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