摘要
目的;观察布比卡因硬膜外麻醉对泮库溴铵肌松时效的影响,为临床减少复合全麻用药提供理论依据。方法:40例行上腹部手术患者,随机分为两组。A组选用泮库溴铵肌松全麻。B组选用泮库溴铵肌松全麻加用布比卡因硬膜外麻醉。分别观察两组泮库溴铵肌松时效。结果:A组和B组泮库溴铵肌松起效时间分别为3.7±0.5分和3.5±0.7分(P>0.05)。无反应期分别为35±4.1分和38±2.3分(P<0.01)。25％NMB恢复时间分别为41±6.7分和48±5.6分(P<0.01)。75％NMB恢复时间分别为71±8.1分和89±6.7分(P<0.01)。恢复指数分别为30.1±1.7和31.1±1.6(P>0.05)。结论:布比卡因硬膜外麻醉可使泮库溴铵肌松时效增强。
Objective:To study the influence of epiduaral anaesthesia with bupivacaine on the effect of pancuronium. Method: forty patients received abdominal surgery, randomly were divided into two groups, general anaesthesia with pancuronium solely (group A)and general anaesthesia with pancuronium with epiduaral anaesthesia with bupivacaine (group B). Results: the onset time in two groups were 3. 7±0. 5min and 3. 5±0. 7min(P>0. 05),respectively;the anergy period were 35±4. 1min and 38±2. 3min(P<0. 01); the 25% recovery time of NMB (Neuro Muscular Blockade,NMB) were 41 ±6. 7min and 48±5. 6min(P< 0. 01),the 75% recovery time of NMB were 71±8. 1min and 89±6. 7min(P<0. 01);the recovery index were 30.1±1. 7 and 31. 3±1. 6(P>0. 05) respectively. Conclusion;epiduaral anaesthesia with bupivacaime can potentiate the NMB effect of pancuronium.
出处
《中国微创外科杂志》
CSCD
1998年第2期4-5,共2页
Chinese Journal of Minimally Invasive Surgery
关键词
布比卡因
硬膜外麻醉
泮库溴铵
肌松
影响
Bupivacaine Epiduaral anaesthesia Pancuronium Relax of muscle Influence.
