摘要
目的:探讨限制性液体复苏治疗创伤性失血性休克的疗效及对炎症因子的影响。方法:选择2008年3月至2011年3月60例创伤性失血性休克患者,随机分为对照组和观察组,每组30例。对照组采用充分液体复苏治疗,观察组应用限制性液体复苏治疗,观察两组患者的术前输液量、红细胞压积、凝血酶原时间、死亡率以及C-反应蛋白、IL-6浓度变化。结果:观察组术前输液量、凝血酶原时间、死亡率、C-反应蛋白、IL-6浓度分别是(1768.79±236.54)ml、(12.14±4.13)s、6.67%、(102.43±33.57)ng/L、(213.49±64.82)ng/L,明显低于对照组的(2876.59±287.34)ml、(17.13±3.94)s、16.67%、(124.67±37.84)ng/L、(275.61±72.35)ng/L,P<0.05。观察组术前红细胞压积是(31.45±3.25)%,显著高于对照组的(24.37±3.69)%,P<0.05。结论:限制性液体复苏治疗创伤性失血性休克临床疗效较好,减轻机体炎症反应,有利于患者康复。
Objective： To observe the effects of limited fluid resuscitation of traumatic hemorrhagic shock on clinical efficacy and inflammatory factors.Methods： A total of 60 patients with traumatic hemorrhagic shock who were selected from March 2008 to March 2011 were randomly divided into control group and observation group,30 patients in each group.The patients were treated with adequate fluid resuscitation in the control group,and the observation group received limited fluid resuscitation.The infusion fluid volume,hematocrit,prothrombin time,mortality,and C-reactive protein concentration,IL-6 concentration were observed before opetation in two groups.Results： The infusion fluid volume,prothrombin time,the mortality rate,C-reactive protein,IL-6 concentrations in the observation group were（1768.79± 236.54）ml,（12.14±4.13）s,6.67%,（102.43±33.57）ng/L,（213.49±64.82）ng/L,that were significantly lower than those {（2876.59±287.34）ml,（17.13±3.94）s,16.67%,（124.67 ±37.84）ng/L,（275.61±72.35） ng/L}in the control group,P 0.05.Hematocrit which was（31.45±3.25）% in the observation group was significantly higher than that {（24.37 ±3.69）%} in the control group,P0.05.Conclusions： Limited fluid resuscitation of traumatic hemorrhagic shock has better clinical efficacy,reduced the inflammatory response.
出处
《价值工程》
2011年第29期306-307,共2页
Value Engineering
关键词
限制性液体复苏
充分液体复苏
创伤性失血性休克
疗效
炎症因子
limited fluid resuscitation
adequate fluid resuscitation
traumatic hemorrhagic shock
clinical efficacy
inflammatory factors
作者简介
陈江（1969-），男，主治医师，从事急诊工作。
