摘要
目的探讨超声造影技术监测氩氦刀治疗恶性肿瘤及评价术后近期疗效的作用。方法 42例患者,在氩氦刀治疗前及治疗后近期采用超声造影技术检查其肿瘤病灶数量、坏死情况,并与常规超声及增强CT或MRI比较。结果共80个病灶,超声造影显示的病灶数及其内部坏死灶的数量(96个vs 19个)和大小(5.7±3.6 cm vs 2.8±1.7 cm)均较常规超声显著增加(P<0.001),与增强CT或MRI显示的坏死灶的数量(94个)和大小(5.5±3.3 cm)比较无统计学差异(P=0.872,0.978),超声造影评价氩氦刀术后近期疗效与增强CT或MRI比较无统计学差异(P=0.906)。结论超声造影在检测氩氦刀治疗恶性肿瘤及评价术后近期疗效中具有重要应用价值。
Objective To assess the value of contrast-enhanced ultrasound imaging in monitoring the therapeutic effect of argon-helium cryosurgical treatment of malignant tumors.Methods Before and after argon-helium cryosurgical treatment,42 patients underwent contrast-enhanced ultrasound imaging,conventional ultrasound imaging and enhanced CT or magnetic resonance imaging（MRI） for examining the number of tumor foci and the size of necrotic areas.Results A total of 80 tumor lesions were detected by contrast-enhanced ultrasound imaging.Compared with conventional ultrasound imaging,contrast-enhanced ultrasound imaging detected a significantly greater number of tumors and the intratumoral necrotic areas（96 vs 19） as well as a significantly increased mean size of necrotic areas（5.7±3.6 cm vs 2.8±1.7 cm）,showing no significant differences from the results by enhanced CT and MRI（94 and 5.5±3.3 cm,P=0.872 and 0.978,respectively）.The short-term therapeutic effect of argon-helium cryosurgery evaluated by contrast-enhanced ultrasound imaging were also similar to that assessed by enhanced CT or MRI（P=0.906）.Conclusion Contrast-enhanced ultrasound imaging has important values in monitoring malignant tumors during argon-helium cryosurgical treatment and in evaluating the short-term therapeutic effect of the treatment.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2011年第9期1622-1625,共4页
Journal of Southern Medical University
关键词
超声造影
氩氦刀
肿瘤
contrast ultrasound imaging
argon-helium cryosurgery system
neoplasms
作者简介
作者简介：刘红梅，博士，副主任医师，副教拨，E—mail：lmelhong@fimmu．com
