摘要
目的探讨美托洛尔治疗不稳定性心绞痛(unstable angina pectoris,UAP)的疗效和安全性。方法 120例UAP患者随机分为对照组和观察组。对照组:硫酸氯吡格雷片;观察组:硫酸氯吡格雷片联合酒石酸美托洛尔。结果观察组总有效率为86.67%高于对照组总有效率71.67%,差异显著(P<0.05)。治疗期间两组患者不良反应率无明显差异,并均无因严重不良反应而中断治疗的病例。结论酒石酸美托洛尔治疗UAP患者疗效可靠,副作用小。
Objective To explore the effect and safety of metoprolol for the treatment of UAP.Methods 120 cases of UAP were divided into the observation group and the control group.The control group was treated with clopidogrel hydrogen sulphate tablets.The observation group was treated with clopidogrel hydrogen sulphate tablets and metoprolol.Results The total effective rate of the observation group was 86.67%,which was higher than 71.67% of the control group,with significant difference（P 0.05）.During the treatment,the patients＇ adverse reaction rate in the two groups had no obvious difference,without interruption treatment cases.Conclusion Metoprolol has good safety,efficacy and reliability for the treatment of UAP.
出处
《临床医学工程》
2011年第9期1370-1371,共2页
Clinical Medicine & Engineering
作者简介
李友年，女，广东梅州人，本科学历，药师，主要从事药物临床研究。
