摘要
目的了解献血人群HIV感染现状及流行趋势,以降低输血风险。方法首先用两家不同的抗-HIV酶联免疫试剂对某地区献血人群进行初筛,初筛阳性标本采用蛋白印迹法确认。结果近10年石家庄地区献血人群总体初筛HIV阳性率为0.204%,总体确认阳性率为0.004%,从2001年的0.004%上升至2010年的0.011%,呈上升趋势(P<0.05);献血人群HIV感染以男性为主,占总感染例数的88.889%;2008-2010年19～29岁年龄段HIV感染15例,占总感染例数的41.667%,有低龄化的趋势,在感染方式上主要为性传播,性感染占总感染例数的75.000%,2008-2010年异性传播9例,同性传播18例,呈现出由异性传播向同性传播转移的趋势。结论为保证输血安全,必须加强无偿献血者,尤其是年轻献血者健康教育的宣传力度,从低危人群中的无偿献血者采集血液并严格检测,提高血液HIV检测的水平,并严格掌握输血适应证。
OBJECTIVE To understand the infection status and trends of the blood donors in the region and reduce the risk of blood transfusion.METHODS The blood donors in the region were tested for HIV antibodys with two different anti-HIV body of ELISA,the positive samples were confirmed by Western blot.RESULTS In nearly a decade the overall positive rate of HIV screening of the blood donors in Shijiazhuang was 0.204%,confirming 0.004%,with the rising tendency from 0.004% in 2001 to 0.011% in 2010.In the region male dominated HIV infection among voluntary blood donation and 88.889% of the total number of infections.There were 15 cases of HIV infection among 19-29 age group during 2008-2010 and 41.667% of the total number of infections,with the trend of younger age.The main way of infection was sexual and 75.000% of the total number of infections,presented by the spread of heterosexual transmission and the shift to same-sex,there were 9 cases of heterosexual transmission and 18 cases of homosexual transmission in 2008-2010.CONCLUSION The need to strengthen voluntary blood donors,especially health education of young blood donors,to collect blood from low risky blood donors and rigorous testing of blood and to improve the sensitivity and specificity of blood HIV test can ensure the safety of blood transfusion,and transfusion indication should be strictly controlled as well.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第17期3568-3570,共3页
Chinese Journal of Nosocomiology
