摘要
本研究对慢性鼻炎（CR）及正常健康人群进行中医气虚辩证，将具有典型与非典型气虚者分别测定鼻腔分泌物中分泌型免疫球蛋白A（SIgA）的含量，结果发现CR及正常健康人群中具有典型气虚者SIgA含量降低，但是CR组与正常组血清免疫球蛋白A、G、M相比差别却无显著性。本研究揭示了CR气虚证与鼻腔局部免疫防御机能低下密切相关，进一步阐明了界分泌物SIgA含量降低为CR气虚证的病理生理学基础之一。
On the basis of Qi-deficiency syndrome (QDS)differentiation in patients with chronic rhinitis (CR) and normal group, typical cases of QDS were determined secretory immunoylobulin A (SIgA) in nasal secretion and compared with that of atypical cases. The results showed that SIgA content in typical cases of QDS attenuated significantly. But a comparison of IgA, IgG and IgM in serum was made between CRgroup and normal group, difference was not obvious. This paper suggested that the close relationship between local hypofunction of immune defense in nasal cavity and QDS with CR was confirmed, and further expounded that the fall of SIgA content in nasal secretion is one of the pathophysiology base of QDS with CR.
出处
《中国中西医结合耳鼻咽喉科杂志》
1999年第4期161-162,共2页
Chinese Journal of Otorhinolaryngology in Integrative Medicine
基金
江苏省中医药管理局科研基金
关键词
慢性鼻炎
免疫学
SIGA
气虚证
Chronic rhinitis Immunology SIgA Qi-deficiency syndrome
