摘要
目的探讨脑利钠肽(BNP)水平变化对心力衰竭的诊断的价值。方法选取我院自2009年6月～2010年6月收治的70例心力衰竭患者及同期在我院健康体检者20例为研究对象,采用酶联免疫吸附法检测两组患者的血清BNP水平,评价BNP水平与心功能状况的关系。结果心衰组BNP水平显著高于对照组,p<0.01,急性心衰BNP水平显著高于慢性心衰,p<0.05。且NYHA心功能分级越高,BNP水平越高,各亚组之间差异显著,p<0.01,发生心血管事件的急性心力衰竭患者的峰值水平较高,p<0.05。结论 BNP水平能较好的反应左心室的功能状态,对心衰者的诊断、预后具有重要临床意义。
Objective To investigate the significance of brain natriuretic peptide（BNP） levels in the diagnosis of heart failure.Methods Select 70 cases with heat failure in our hospital from June 2009 to June 2010 and 20 cases for health check in the same period as study object.Determine the level of serum BNP of the two groups by means of enzyme-linked immunosorbent assay.Evaluate the relation between BNP level and heart function.Results BNP levels in heart failure group were significantly higher,p0.05.BNP level in acute heart failure is significantly higher than chronic heart failure,p0.05.And in higher NYHA functional class,BNP level is higher,the differences between the subgroups were significantly,p0.05,acute cardiovascular events in patients with heart failure higher peak levels,p0.05.Conclusion BNP levels can be a better response to left ventricular functional status,thus in heart failure diagnosis and prognosis it has important clinical significance.
出处
《现代医院》
2011年第6期41-42,共2页
Modern Hospitals
关键词
脑利钠肽
心力衰竭
诊断
预后
Brain natriuretic peptide
Heart failure
Diagnosis
Prognosis
