摘要
目的:探讨左卡尼联合黄芪注射液治疗急性病毒性心肌炎(acute viral myocarditis,AVM)的临床疗效。方法:将78例AVM患者随机分为观察组与对照组,每组各39例,对照组给予极化液(5%葡萄糖盐水500ml+10%氯化钾10ml+胰岛素6U)和能量合剂(10%葡萄糖500ml+ATP40mg)静脉滴注,1次/d,加用黄芪注射液50ml/d。观察组则在对照组基础上加用左卡尼汀2～3g/d,注入5～10%葡萄糖100～250ml/d静滴,两组28d为1个疗程。观察患者症状、心电图、胸片及心脏超声所示的心脏大小及心功能改变、心肌酶学指标、肌钙蛋白的变化,并评价其疗效。结果:观察组总有效率为94.87%,对照组则为79.49%,两组比较差异有统计学意义(P<0.05)。结论:左卡尼汀联合黄芪注射液使用对AVM具有较好疗效。
Objective：To discuss the clinical curative effect of levocarnitine combined with astragalus mongholicus injection treatment for acute viral myocarditis.Methods：78 cases with AVM were randomly divided into observation group and control group,every group for 39 cases,the control group were treated with polarized solution（5 percent glucose saline 500 milliliters ＋ 10 percent kalium chloratum 10 milliliters ＋ insulinum 6 U） and energy mixture（10 percent glucose saline 500 milliliters ＋ ATP 40 mg） intravenous drip,once a day,added astragalus mongholicus injection 50 milliliters every day.On the basis of the control group,the observation group were treated with levocarnitine 2-3 g every day,emptied into 5-10 percent glucose saline 100-250 milliliters and intravenous drip,all treated for 28 days,one course of treatment.Observed the symptom,electrocardiogram,chest radiograph and cardiac ultrasonic contrast about the size and the change of the heart function,cards cardiac enzymes target,the change of the troponin,appraised curative effects.Results：The total effective rate of observation group was 94.87%,the control group was 79.49%,there were different statistical significance between the two groups（P0.05）.Conclusion：The levocarnitine combined with astragalus mongholicus injection has better curative effects.
出处
《中国当代医药》
2011年第18期27-29,共3页
China Modern Medicine
关键词
急性病毒性心肌炎
左卡尼汀
黄芪注射液
疗效观察
Acute viral myocarditis
Levocarnitine
Astragalus mongholicus injection
Efficacy
