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地佐辛超前镇痛用于腰椎间盘突出症患者术后镇痛效果观察 被引量:13

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摘要 目的 观察地佐辛超前镇痛用于腰椎间盘突出症患者术后镇痛效果.方法 选择ASAⅠ~Ⅱ级择期行腰椎板减压、椎弓根内固定手术患者90例随机分为三组,每组30例.A组:术前10 min静注地佐辛0.1 mg·kg-1和术后地佐辛0.8 mg·kg-1持续静脉镇痛;B组:术毕前10 min静注地佐辛0.1 mg·kg-1和术后地佐辛0.8 mg·kg-1持续静脉镇痛;C组:术后地佐辛1.0 mg·kg-1持续静脉镇痛.三组静脉镇痛泵中均加入注射用盐酸昂丹司琼8 mg及生理盐水总共配制成100 ml(泵注速率2 ml·h-1).观察三组患者术后2、6、12、24、48 h视觉模拟评分(VAS)、舒适度评分(BCS)和镇静程度评分(Ramesy)及不良反应.结果 A、C组各时点的VAS评分均低于B组(P〈0.05),A、B组术后12、24 h的Ramesy评分明显低于C组(P〈0.05),BCS评分组间比较数值近似(P〉0.05).结论 地佐辛超前镇痛可减少术后静脉镇痛的用药量,且不良反应少.
出处 《安徽医药》 CAS 2011年第7期895-896,共2页 Anhui Medical and Pharmaceutical Journal
作者简介 通讯作者 杨程,男,副主任医师,研究方向:临床麻醉,E-mail:poweryc@126.com
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