摘要
观察右美托咪啶复合罗哌卡因经肌问沟在超声引导下行臂丛神经阻滞的临床效果。方法选择择期行上肢手术的40例患者，随机分成两组，每组20例。在超声引导下行肌间沟臂丛神经阻滞，D组给予0．5％罗哌卡因20ml加右美托咪啶1μg／kg，C组仅给予0．5％罗哌卡因。观察并记录感觉和运动神经阻滞起效时间、持续时间，以及不同时间点的MAP、HR、SpO2及Ramsay评分。观察并记录不良反应。结果D组患者的感觉神经阻滞起效时间明显短于C组，感觉和运动神经阻滞持续时间明显长于C组（P〈0．05）；在T1、T2、T3时间点，D组患者的MAP低于C组（P〈0．05）；HR明显慢于C组（P〈0．01）；在T1、T2、T3时间点，D组患者的Ramsay评分明显升高，且高于C组（P〈0．01）。结论右美托咪啶复合罗哌卡因在超声引导下行臂丛神经阻滞，可明显缩短感觉神经阻滞起效时间，延长感觉、运动神经阻滞持续时间，有利于维持血流动力学的稳定。
Objective To observe the effect of dexmedetomidine combined with ropivacaine on intersealene braehial plexus block under the guidance of ultrasound. Methods Forty patients scheduled for upper limb surgery under ultrasound guidance to block the intersealene braehial plexus were randomly assigned to two groups. In group D（n= 20） the patients were received ropivaeaine and dexmedetomidine, and in group C（n= 20） received with only ropivaeaine. Motor and sensory block onset times and block durations were recorded. BP, heart rate, SpO2 and Ramsay score were monitored at different time points. Adverse events were recorded. Results Sensory block onset time in group D were significantly shorter than that in group C（P〈0.05）. Sensory and motor block durations in group D were longer than that in group C（P〈0.05）. Mean arterial pressure（MAP） and heart rate in group D were lower than those in group C（P〈0.05）, Ramsay score in group D were higher than that in group C（P〈0. 01）. In group D, bradycardia was observed in 5 patients, hypotension in 4 patients. The difference between the two groups was statistically significant（P〈0.05）. Conclusions Dexmedetomidine added to ropivaeaine for intersealene braehial plexus block guided by ultrasound may shorten the onset time of sensory block, prolongs the duration of sensory and motor block,which benefits the steady hemodynamies.
出处
《实用疼痛学杂志》
2011年第2期102-105,共4页
Pain Clinic Journal
作者简介
通讯作者：马瑞，Email：marui100@hotmail．com
