摘要
目的 探讨欣普贝生用于妊娠晚期促宫颈成熟的有效性和安全性.方法 按对照研究的方法,将60例妊娠晚期、无阴道分娩禁忌、单胎头位的孕妇随机分为阴道放置欣普贝生的研究组和小剂量催产素静滴的对照组,比较2组用药前及用药6,12h后的B ishop评分,以及分娩方式的影响.结果 欣普贝生组给药12h Bishop评分能提高2.25±1.46,促宫颈成熟效果达90%,临产时间为（7.05±4.52）,总产程时间为（8.9±3.07）,剖宫产率降至13.33%,2组比较有显著性差异（ P〈 0.05）,.结论 欣普贝生是一种安全有效的促宫颈成熟的药物,降低剖宫产率效果显著.
Objective To inquire/evaluate the validity and safety of dinoprostone for cervical ripening. Methods 60 single term pregnant women without any vaginal delivery taboo and normal location were randomly divided into two group, 30 cases in dinoprostone group,30 cases in oxytocin group.The Bishop score of cervical and their influence on the birth process were compared. Results Dinoprostone could raise the Bishop cervical scale by （2.25±1.46） score, the efficiency to promote the ripeness of cervix could reach 90%,the parturient time（7.05±4.52）,the total labor stages were（8.9±3.07）,the rate of cesarean operation dropped to 13.33%. The efficiency in study group were higher than that in the control group. Conclusion Dinoprostone is effective in producing cervical ripening and induce labor.
作者
姜广利
王保莲
毕冬华
JIANG Guang-li,WANG Bao-lian,BI Dong-hua （Xinxiang Centre Hospital in I-lenan Province,Xinxiang 453000,China）
出处
《医学信息》
2011年第12期3720-3721,共2页
Journal of Medical Information
