摘要
目的观察米力农治疗慢性心力衰竭急性加重期的临床疗效。方法 92例慢性心力衰竭患者随机分为两组。A组使用洋地黄、ACEI、利尿剂、硝酸脂类等药物常规治疗;B组在A组基础上,加用米力农静脉滴注,观察疗程2周。对比两组左室射血分数(LVEF)、左室舒张末期内径(LVDd)、心率、血压、临床心功能NYHA分级的改变及药物不良反应。结果两组患者治疗2周后心功能均有显著改善,治疗前后差异具有统计学意义(P<0.05),B组与A组相比,患者心率减慢,血压、LVDd降低,LVEF升高的幅度更显著(P<0.05),差别有显著性。结论米力农治疗慢性心力衰竭急性加重期,临床疗效显著且安全可靠。
Objective To observe the clinical curative effect of Milrinone in chronic heart failure acute exacerbation period.Methods Ninety-two patients with chronic heart failure were randomly divided into two groups,A group with routine treatment such as digitalis,ACEI,diuretics and lipid nitrate drugs.On the basis of the A group,B group was given intravenous infusion of Milrinone and then it was observed for 2 weeks.Two groups were compared in left ventricular ejection fraction（LVEF）,left ventricular end diastolic diameter（LVDd）,heart rate,blood pressure,NYHA classification of clinical changes in heart function and adverse drug reactions.Results After 2 weeks of treatment,both groups had significantly improved heart function after treatment,the difference was significant（P0.05）.Compared with A group,heart rate,blood pressure,and LVDd of patients in B group decreased,and LVEF increased（P0.05）.Conclusion Milrinone has significant clinical efficacy and safety in acute exacerbation of chronic heart failure.
出处
《实用临床医药杂志》
CAS
2011年第9期86-87,102,共3页
Journal of Clinical Medicine in Practice
