摘要
目的初步评价新型血流导向装置Tubridge治疗颅内动脉瘤的可行性、疗效和安全性。方法前瞻性收集Tubridge血流导向装置治疗的14例患者共14枚动脉瘤的临床资料。14枚动脉瘤中未破裂动脉瘤13枚,破裂动脉瘤1枚。结果本组共植入18枚血流导向装置,均成功输送并释放,技术成功率100%。6枚动脉瘤采取血流导向装置结合弹簧圈栓塞治疗,即刻栓塞结果按Raymond分级,Ⅰ级2例,Ⅱ级1例,Ⅲ级3例;8枚动脉瘤单纯采取血流导向装置治疗,3枚动脉瘤术后瘤体充盈体积明显减少,所有动脉瘤的造影剂充盈方式改变,瘤内对比剂明显滞留。本组未发生技术相关出血性和缺血性并发症,出院时mRS评分0分13例,1分1例。结论 Tubridge血流导向装置治疗部分特殊类型颅内动脉瘤,即刻疗效满意,短期内安全性高,长期疗效和安全性有待于进一步评价。
Objective To preliminarily evaluate the feasibility,efficacy and safety of the novel flow diverting device,Tubridge,in treating intracranial aneurysms.Methods The novel flow diverting device,Tubridge,was employed to treat intracranial aneurysms in 14 patients with a mean age of（52.4 ± 10.2） years.A total of 14 intracranial aneurysms were detected in 14 patients,including 13 un-ruptured aneurysms and one ruptured aneurysm.The technical results and clinical data were analyzed.Results A total of 18 flow diverters were implanted.The flow diverter was successfully conveyed and delivered in all patients,with a technical success rate of 100%.Six aneurysms were treated with the flow diverter together with the coils.Of the six aneurysms,complete obliteration of the aneurysm was obtained in 2（Raymond grade I）,remnant of neck was seen in 1（Raymond grade II） and residual aneurysm sac was found in 3（Raymond grade III） cases.Eight aneurysms were treated with flow diverter implantation alone.After the procedure,marked decrease in contrast filling of the aneurysm sac was seen in 3 aneurysms,while the change in contrast filling pattern of the aneurysm sac as well as the obvious retention of contrast in the aneurysm sac could be detected in all cases.No procedure-related hemorrhagic or ischemic complications occurred.The mRS score at the time of discharge was 0（n = 13） or 1（n = 1）.Conclusion For the treatment of some special type intracranial aneurysms,the use of Tubridge flow diverter is clinically feasible,its effect is immediate and satisfactory with higher safety in short term.However,its long-term efficacy and safety need to be further evaluated.
出处
《介入放射学杂志》
CSCD
北大核心
2011年第5期357-362,共6页
Journal of Interventional Radiology
基金
上海市科委项目(10441901902)
军队临床高新技术项目(2010gxjs058)资助
关键词
颅内动脉瘤
介入治疗
血流导向装置
intracranial aneurysm
interventional treatment
flow diverter
作者简介
通信作者：刘建民
