摘要
对133例药疹伴感染病例的致敏药物和抗生素使用情况进行分析。结果显示抗生素是最常见的致敏药物,其中又以青霉素类多见,其次为头孢菌素类、喹诺酮类和氨基糖苷类,磺胺类引起的致敏也较常见。在133例中,选用大环内酯类抗生素作抗感染治疗最多,有效率达88.24%,未见出现过敏反应。对伴有感染的药疹选用大环内酯类作抗感染治疗是安全、有效的。
One hundred thirty three
cases of drug eruption complicated infections were analyzed. It showed that the most common
causative drug were antibiotics. Of which penicillins were most frequently found, then
cephalosporins, quinolones and aminoglycosides. Sulfa drugs were also commonly
encountered. 68 of 133 cases were treated with macrolides for the infections. Result showed
that clinical efficacy rate was 88.24% and no case had allergic reaction. It is suggested that
macrolides are effective and safe for the anti infective treatment, and could be thought of as
first line antibiotics on the drug eruption.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1999年第4期300-301,316,共3页
Chinese Journal of Antibiotics