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万福液镇痛止痒作用的药效学研究

Wanfu liquid antipruritic effect of analgesic efficacy studies
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摘要 目的:观察万福液对实验性小鼠痛阈及对豚鼠致痒阈的影响,阐明其镇痛止痒的作用特点。方法:采用小鼠热板法进行镇痛试验,采用磷酸组胺致豚鼠足痒的方法进行止痒试验。结果:万福液能明显抑制小鼠热刺激所致的疼痛,且具有抗组胺致痒的作用,提高致痒阈,降低其反应性。结论:万福液具有镇痛止痒作用。 Objective:To observe Wanfu liquid on experimental pain threshold in mice and guinea pigs induced itch threshold effect, clarify the characteristics of its analgesic effect of itching. Methods:Mice were hot plate analgesia test, guinea pigs by histamine phosphate method itch itching foot test. Results:Wanfu solution could inhibit the pain caused by thermal stimulation in mice, and had anti-histamine induced itch, and improved itching threshold, reduced its reactivity. Conclusion:Wanfu solution has analgesic effects itching.
出处 《中国当代医药》 2011年第15期16-16,18,共2页 China Modern Medicine
关键词 万福液 镇痛 止痒 药效学 Wanfu liquid Analgesic Itching Pharmacodynamics
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