摘要
考察了ＤＬ聚乳酸（ＤＬＰＬＡ）／甲壳素（ＣＨＩ），ＤＬＰＬＡ／甲壳胺（ＣＨＳ）两种复合物在生理盐水降解过程中生理盐水的ｐＨ 值、试样的失重率和外观形态以及ＤＬＰＬＡ 分子量的变化，结果表明：ＣＨＩ和ＣＨＳ对ＤＬＰＬＡ 的降解速度有明显的抑制作用，并对抑制机理进行了探讨。
The authors assessed the variations of pH values of the physiological saline used for in vitro degradation tests of DL Polylactide(DL PLA)/chitin and DL PLA/chitosan composites and DL PLA. The weight loss rations, the appearance and morphology of the tested specimens, and the molecular weights of DL PLA in composites and pure DL PLA were alse investigated. The results showed that both chitin and chitosan had significant inhibitory effects on the degradation of DL PLA, and the effect of chitosan was stronger than that of chitin. A discussion on the mechanism of such inhibition is presented.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
1999年第3期267-270,共4页
Journal of Biomedical Engineering
基金
广东省自然科学基金
关键词
DL-聚乳酸
甲壳素
甲壳胺
体外降解
DL Polylactide Chitin Chitosan Degradation in vitro Retardation
