摘要
目的:考察临床药师干预腹股沟疝修补术患者围术期抗菌药物应用的效果。方法:分别抽取我院2009年8-12月(干预前)和2010年8-12月(干预后)的腹股沟疝修补术出院患者病历各60份。对围术期预防性应用抗菌药物适应证、药物选择、用法用量、给药时机与疗程、联合用药、通用名书写等方面合理性进行比较。结果:经临床药师干预,腹股沟疝修补术患者围术期预防性应用抗菌药物在药物选择、用法用量、联合用药、用药时机与疗程、通用名书写、病历中抗菌药物用药分析等方面较干预前均有明显改善,住院药品费用占总费用的比例由27.66%下降到22.62%,抗菌药物费用占总药品费用的比例由20.88%降至8.07%。抗菌药物应用时间由2.38d下降至0.95d。结论:临床药师对腹股沟疝修补术围术期预防性应用抗菌药物的干预是可行并且有效的,对Ⅰ类切口围术期预防性用药的安全、有效、合理、经济具有积极的促进作用。
OBJECTIVE： To investigate the effect of clinical pharmacists intervening in prophylactic application of antibiotics during perioperative period of inguinal herniorrhaphy. METHODS： 60 discharged medical records were collected from our hospital during Aug.-Dec. in 2009 （before intervention） and Aug.-Dec. in 2010 （after intervention）, respectively. The rationality of perioperative prophylactic application of antibiotics was compared in terms of antibiotics indication, medicine selection, usage and dosage, administration time and treatment course, drug combination, handwriting of generic name, etc. RESULTS： After intervention of clinical pharmacists, the perioperative prophylactic application of antibiotics was improved significantly in respects of medicine selection, dosage and usage, drug combination, administration time and treatment course, handwriting of generic name, analysis of antibiotics use in case history. The percentage of total drug cost in total hospitalization costs decreased from 27.66% to 22.62%, and the proportion of total cost of antibiotics in total drug cost decreased from 20.88% to 8.07%. Total hospitalization day of antibiotic use decreased from 2.38 d to 0.95 d. CONCLUSIONS： It is effective and practicable for clinical pharmacists to interven in prophylactic application of antibiotics during perioperative period of inguinal herniorrhaphy. The intervention of clinical pharmacists contributes to the safe, effective, reasonable and economic use of antibiotics.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第22期2095-2097,共3页
China Pharmacy
基金
山东省药学会奥赛康中青年科研资助项目(2010-07)
关键词
腹股沟疝修补术
合理用药
抗菌药物
干预研究
Inguinal herniorrhaphy
Rational drug use
Antibiotics
Intervention study
作者简介
副主任药师，硕士。研究方向：临床药学。电话：0532—82911767。E—mail：buxie75@163．com
通讯作者：副主任药师，硕士。研究方向：临床药学与药事管理。电话：0532-82911277。E-mail：jidi1767@126．com
