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定期多次单采血小板捐献者血清铁蛋白状况分析 被引量:14

Serum Ferritin in Donors with Regular Plateletpheresis
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摘要 本研究分析定期多次捐献单采血小板对血清铁的影响。随机抽取本站男性首次单采血小板捐献者24例和定期多次单采血小板捐献者69例,用ELISA法检测其血清铁蛋白(SF)含量。结果表明,首次单采血小板捐献者和定期多次单采血小板捐献者的SF含量分别为91.08±23.38μg/L和57.16±35.48μg/L,但均在正常值范围内,两者之间的差异具有统计学意义(p<0.05)。SF含量随血小板捐献频率的增加而下降,但各捐献频率组之间的差异均不具有统计学意义(p>0.05)。随血小板捐献次数的增加,SF含量呈现波动性的变化。结论:定期多次捐献单采血小板可导致SF减少。 This study was aimed to evaluate the impact of regular donating platelets on serum ferritin(SF) of donors.A total of 93 male blood donors including 24 initial plateletpheresis donors and 69 regular plateletpheresis donors were selected randomly.Their SF level was measured by ELISA.The results showed that the SF level of initial plateletpheresis donors and regular plateletpheresis donors were 91.08±23.38 μg/L and 57.16±35.48 μg/L respectively,and all were in normal levels,but there was significant difference between the 2 groups(p〈0.05).The SF level decreased when the donation frequency increased,there were no significant differences between the groups with different donation frequency.Correlation with lifetime donations of platelets was not found.It is concluded that regular plateletpheresis donors may have lower SF level.
机构地区 佛山市中心血站
出处 《中国实验血液学杂志》 CAS CSCD 2011年第2期508-510,共3页 Journal of Experimental Hematology
基金 佛山市医学科学技术研究计划项目 编号2011190
关键词 单采血小板 血小板捐献者 血清铁蛋白 apheresis platelet platelet donor serum ferritin
作者简介 通讯作者:郭如华,主任技师.电话:(0757)83031698。E—mail:hnguorh@yahoo.com.cn
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参考文献7

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