摘要
目的：探讨青年组（14~44岁）和老年组（60岁以上）2型糖尿病患者的牙周健康状况与血糖控制、体质量指数及血脂水平的关系。方法：选取2型糖尿病住院患者229例,分为青年组和老年组进行研究,检查患者的牙周情况,并于入院后所有患者取血测糖化血红蛋白（HbA1c）、总胆固醇（TC）、三酰甘油（TG）及体质量指数（BMI）。比较2年龄组的牙周健康状况与血糖控制水平、肥胖及血脂水平的关系。结果：2组高TC、高TG、高HbA1c、超重及肥胖构成比较差异有统计学意义（P〈0.001或P〈0.05）。青年组、老年组的多因素Logistic回归分析显示,高HbA1c、高TG、超重、肥胖为青年组2型糖尿病患者牙周病发病的主要危险因素;高TC、高HbA1c为老年组2型糖尿病患者牙周病发病的主要危险因素。结论：在2型糖尿病患者中,血糖控制差、肥胖和TG的升高是青年人群牙周病发病的主要危险因素,控制血糖和TC是降低老年人群牙周病发病率的重要措施。
Objective：To investigate the correlation between the periodontal health, blood glucose, weight index and blood lipid in patients with type 2 diabetes, especially in the youth patients （aged 14-44） and the elderly patients （60 years old or above）. Methods：The selected hospitalized patients with type 2 diabetes （n=229） were divided into two groups, the youth group and the senior group. The periodontal health and values of glycated hemoglobin （HbA1c）, total cholesterol （TC）, triglyceride （TG） and body-mass index （BMI） were detected. A database was established with the help of software named Epdata. The correlation between the periodontal health, glycemic index, weight index and lipid level was compared with SPSS 14.0 packages between the two groups. Results：The levels of TC, TG and HbA1c, and the value of body weight were significantly different between the two groups （P〈 0.001 or P〈 0.05）. All the above factors were associated with periodontal disease in patients with type 2 diabetes. The logistic regression analysis showed that the higher levels of HbA1c and TG, overweight and obesity were the major risk factors for periodontal disease in youth group. While the major risk factors for periodontal disease were the higher levels of TC and HbA1c in the senior group. Conclusion：For the young patients with type 2 diabetes, the poor blood glucose control, obesity and increased triglyceride are the major risk factors for periodontal disease. The best prophylactic measure for aging population to reduce the incidence of periodontal disease is to control both blood glucose and total cholesterol.
出处
《天津医药》
CAS
北大核心
2011年第3期221-223,共3页
Tianjin Medical Journal
