摘要
目的 分析2010年EV71感染死亡病例的临床特征，为早期识别和救治危重症病例积累资料。方法收集并整理2010年湖北省四地区6例手足口死亡病例的临床资料。结果6例死亡病例中，男5例，女1例。年龄7～38个月，5／6的病例小于3岁。起病到确诊时间为1～2d，确诊至病情加重转院时间为1天，转诊后12小时内死亡4例。6例均表现为持续高热，手、足、口和肛周等部位疱疹，危重表现为脑炎和肺水肿。给与呼吸机支持，但最终均死于呼吸循环衰竭。结论EV71感染死亡病例主要见于3岁以内婴幼儿，病情进展迅速，应及早给与呼吸机辅助通气和足量IVIG。
Objective To analyze the clinical features and accumulate the experiences for early recognition and treatment of death cases associated to severe EV71 infection. Methods Collecting the clinical documents of 6 cases died of HFMD in year 2010 from 4 different districts in Hubei province. Results of six died patients, male 5 and female 1, age range from 7 months to 38 months and 5 cases younger than 3 years old. The time from onset to diagnosed is 1 -2 days and from diagnosed to the appearance of severe signs is 1 day,and 4 cases died in 12hrs after transferred to the general hospitals for local HFMD patients. All six patients had the manifestations of hyperthemic and rashes in hand, foot, mouth and ass and progressed to severe with signs of encephalitis, pulmonary edema and hemorrhage. Despite of using the treatmentwith mechanical ventilation, all six patients died of cardiopulmonary failure within 3 days. Conclusion Severe EVT1 infection mainly causes death in children younger than 3 years old, early respiratory assistance and high dose of IVIG should be critically urged during the progress of pulmonary edema.
出处
《医学新知》
CAS
2011年第1期26-29,共4页
New Medicine
作者简介
通信作者：赵东赤，E—mail：zhao—wh2004@hotmail．com
