摘要
目的评价加替沙星滴眼液与左氧氟沙星滴眼液治疗急性细菌性角膜炎感染的经济学效果。方法根据文献,急性细菌性角膜炎患者112例分为两组,分别用加替沙星滴眼液和左氧氟沙星滴眼液治疗,应用药物经济学的成本-效果分析法进行分析。结果加替沙星与左氧氟沙星的临床总有效率分别为95.1%与76.9%(P<0.05);成本-效果比分别为73.61和29.91。结论在治疗急性细菌性角膜炎方面,加替沙星滴眼液有较好的疗效和潜在的血糖异常等严重不良反应。然而,左氧氟沙星滴眼液的成本-效果优于加替沙星滴眼液。
OBJECTIVE To evaluate the cost-effectiveness of gatifloxacin and levofloxacin eye drops in treatment of acute bacterial keratitis.METHODS One hundred and twelve patients with acute bacterial keratitis were randomLy divided into gatifloxacin and levofloxacin groups treated by gatifloxacin and levofloxacin,and were evaluated with cost-effectiveness analysis.RUSULTS The efficacy rates of gatifloxacin and levofloxacin in treatment of acute bacterial keratitis were 95.1% and 76.9%（P0.05）,and the corresponding cost-effectiveness were 73.61 and 29.91,respectively.CONCLUSION In the treatment of acute bacterial keratitis,gatifloxacin eye drops have better effect and serious adverse reactions of potential glucose,etc.However,the cost-effectiveness of levofloxacin eye drops is superior to gatifloxacin eye drops.
出处
《海峡药学》
2010年第12期261-264,共4页
Strait Pharmaceutical Journal
作者简介
章桂芳,女（1972-）.职称：主管药师,主要从事医院药学工作.联系电话：13912313608,E-mail：zhangguifang1972@163.com
