摘要
背景午睡在国内外是一种普遍现象,其对心脑血管疾病的利弊影响尚无定论。目的探索午睡频率与血压及中老年人高血压的关系。方法以《广州生物库队列》招募的30518名受检者为研究对象,通过标准化问卷收集其一般人口学特征、生活方式、午睡频率、打鼾、睡眠总时间以及个人健康状况等,并进行包括身高、体质量、腰围、血压、血脂和空腹血糖等检测,以此基线资料为基础进行横断面研究。结果①在调整潜在混杂因素包括年龄、性别、教育、职业、吸烟、体力活动、腰围、空腹血糖、三酰甘油、高与低密度脂蛋白胆固醇、打鼾和睡眠总时间后,全部受检者的收缩压、舒张压和平均动脉压随午睡频率增加而升高(F值分别为4.0、6.3和5.6,P<0.05或<0.01,线性趋势均P<0.01);对于自报一般健康状况好的受检者的收缩压、舒张压及平均动脉压同样随午睡频率增加而升高(F值分别为4.4、6.6和6.1,均P<0.01,线性趋势值也均P<0.01);②调整上述潜在的混杂因素后,相对于不午睡或<1d/周组,高血压的比值比(95%CI)在1～3和≥4d/周分别为1.05(0.97～1.14)和1.16(1.09～1.22),线性趋势检验P<0.01。结论午睡频率与中老年人高血压患病率呈正相关。
Background The siesta is a common phenomenon at home and abroad,but it is still unclear whether siesta has advantages or disadvantages for cardiovascular and cerebrovascular diseases.Objective To explore the association between siesta frequency and blood pressure and hypertension in the middle-aged and elderly.Methods In 30 518 subjects from the Guangzhou Biobank Cohort Study,information on demographic characteristics,lifestyle,siesta frequency,total sleep duration,snoring and disease history were collected by a standardized questionnaire,and data including height,weight,waist circumference,blood pressure,lipids and fasting glucose were also monitored.Cross-sectional study based on the above baseline information was performed.Results ① Systolic blood pressure（SBP）,diastolic blood pressure（DBP）and mean arterial pressure（MAP）rose remarkably with increasing siesta frequency in all cases after adjusting for the potential confounding variables including age,sex,education,occupation,smoking,alcohol use,physical activity,waist circumference,fasting glucose,triglycerides,high-and low-density lipoprotein cholesterol,snoring and total sleep duration（F=4.0,6.3 and 5.6 respectively,P〈0.05 or P〈0.01 and P〈0.01 for linear trend）;SBP,DBP and MAP also went up with increasing siesta frequency in those subjects with good self-rated health（F=4.4,6.6 and 6.1 respectively,all P〈0.01 and P〈0.01 for linear trend）;②After adjusting for potential confounders,the odds ratios（95% CI）of hypertension were 1.05（0.97-1.14）and 1.16（1.09-1.22）respectively in those subjects who took a siesta once to thrice a week and those took more than four times a week compared to those who never had a noon nap or those had less than once a week（P〈0.01 for linear trend）.Conclusion The siesta frequency was positively associated with hypertension prevalence in the middle-aged and elderly.
出处
《中华高血压杂志》
CAS
CSCD
北大核心
2011年第1期47-51,共5页
Chinese Journal of Hypertension
基金
广州市科技局重点资助项目(2002Z2-E2051)
香港大学科研教育基金会
英国伯明翰大学医学院
广州市卫生局提供资助
关键词
午睡频率
中老年人
高血压
Siesta frequency
The middle-aged and elderly
Hypertension
作者简介
通信作者：江朝强，E-mail：jcqiang@21cn．com
