摘要
采用溶液共混法将不同含量纳米羟基磷灰石(n-HA)充填于聚乙丙交酯(PLGA)制得n-HA/PLGA纳米复合材料,用差示扫描量热法(DSC)研究了该复合材料的等温结晶行为并采用Avrami方程处理等温结晶过程,计算结晶动力学参数。结果表明,该n-HA/PLGA复合材料体系结晶速度快慢的温度大部分符合110℃>100℃>120℃>90℃>130℃关系;在同一结晶温度下,n-HA对PLGA起到异相成核的作用,使复合材料的结晶速率大大提高,半结晶时间t1/2明显缩短,结晶速率大小基本上为3%n-HA>10%n-HA>1%n-HA>5%n-HA>PLGA。
Nano-hydroxyapatite（HA）/ poly-lactic-co-glycolic acid（PLGA） composites with different n-HA contents were prepared by co-solution method.The kinetics of isothermal crystallization of n-HA/PLGA composites have been investigated by differential scanning calorimetry（DSC）.The Avrami equation has been used to analyze isothermal crystallization,and the correlative kinetics parameter values were given.The results show that crystallization temperature（Tc） is one of important factors,and the crystallization rate is accord with the relational expression of 110 ℃100 ℃120 ℃90 ℃130 ℃.On the other hand,in the same Tc,the presence of n-HA acts as nucleate and enhances greatly the crystallization rate of PLGA,and the parameter value of the half-time for crystallization（t1/2） is obvious shortened.Moreover,the crystallization rate is by and large based on the formula of 3% n-HA 10% n-HA 1% n-HA 5% n-HAPLGA.
出处
《高分子材料科学与工程》
EI
CAS
CSCD
北大核心
2011年第3期71-75,共5页
Polymer Materials Science & Engineering
基金
中国科学院“西部之光”人才培养计划资助项目
关键词
聚乙丙交酯
纳米羟基磷灰石
等温结晶
poly-lactic-co-glycolic acid
nano-hydroxyapatite
isothermal crystallization
作者简介
通讯联系人：蒋泖云，主要从事生物材料的研究，E—mail：jlytxg@163．com
