期刊文献+

中西医结合治疗早期糖尿病肾病的临床研究 被引量:5

在线阅读 下载PDF
导出
摘要 目的:观察使用具有益气养阴、活血化瘀功效的中药针剂治疗早期糖尿病肾病的临床疗效。方法:将63例早期糖尿病肾病患者随机分为治疗组和对照组。治疗组32例,以参麦、黄芪、丹参注射液3组加饮食控制和西医基础治疗;对照组31例,采用饮食控制和西医基础治疗。观察2组临床疗效(24 h尿蛋白定量测定、空腹血糖测定)。结果:2组总有效率比较治疗组优于对照组(P<0.01),差异有统计学意义,治疗组在降低24 h尿蛋白方面优于对照组(P<0.01)。结论:中西医结合治疗早期糖尿病肾病有较好的临床疗效。
作者 谢滨
机构地区 南宁市中医院
出处 《长春中医药大学学报》 2011年第1期31-32,共2页 Journal of Changchun University of Chinese Medicine
作者简介 谢滨(1962-),大学本科,副主任医师。研究方向:中西医结合防治糖尿病及其并发症的临床研究。
  • 相关文献

参考文献4

二级参考文献17

  • 1Matsunaga-Irie S,Maruyama T,Yamamoto Y,et al.Relation between development of nephropathy and the p22phox C242T and rreceptor for advanced glycation end product G1704T gene polymorphisms in type 2 diabetic patients.Diabetes Care,2004,27(2):303-307
  • 2Pettersson-Fernholm K,Forsblom C,Hudson BI,et al.The functional-374 T/A RAGE gene polymorphism Is associated with proteinuria and cardiovascular disease in type 1 diabetic patients.Diabetes,2003,52(3):891-894
  • 3Zhao HL,Tong PC,Lai FM,et al.Association of glomerulopathy with the 5'-end polymorphism of the aldose reductase gene and renal insufficiency in type 2 diabetic patients.Diabetes,2004,53(11):2984-2991
  • 4Lajer M,Tarnow L,Fleckner J,et al.Association of aldose reductase gene Z+2 polymorphism with reduced susceptibility to diabetic nephropathy in Caucasian type 1 diabetic patients.Diabet Med,2004,21(8):867-873
  • 5Hodgkinson AD,Millward BA,Demaine AG.Polymorphisms of the glucose transporter gene are associated with diabetic nephropathy.Kidney Int,2001,59(3):985-989
  • 6Ng DP,Canani L,Araki S,et al.Minor effect of GLUT1 polymorphisms on susceptibility to diabetic nephropathy in type 1 diabetes.Diabetes,2002,51(7):2264-2269
  • 7Luik PT,Hoogenberg K,Kerstens MN,et al.The influence of the ACE (I/D)polymorphism on systemic and renal vascular responses to angiotensins in normotensive,normoalbuminuric type 1 diabetes mellitus.Diabetologia,2003,46(8):1131-1139
  • 8Solini A,Dalla VM,Saller A,et al.The angiotensin-converting enzyme DD genotype is associated with glomerulopathy lesions in type 2 diabetes.Diabetes,2002,51:251-255
  • 9Noiri E,Satoh H,Taguchi J,et al.Association of eNOS Glu298Asp polymorphism with end-stage renal disease.Hypertension,2002,40(4):535-540
  • 10Ksiazek P,Wojewoda P,Muc K,et al.Endothelial nitric oxide synthase gene intron 4 polymorphism in type 2 diabetes mellitus.Mol Diagn,2003,7(2):119-123

共引文献848

同被引文献74

  • 1魏佳莉,彭佑铭,王建文,刘丽萍,李霞.139例2型糖尿病肾病患者血脂代谢异常与肾损害(英文)[J].中国现代医学杂志,2004,14(15):28-31. 被引量:23
  • 2曹卫芬.肾功能不全患者的糖尿病治疗[J].糖尿病天地·临床刊,2012,11,6(11):514-518.
  • 3Cheung BM,Ong KL,Chemy SS,et al.Diabetes prevalence and therapeutic target achievement in the United States,1999 to 2006[J].Am J Med,2009,122(5):443-453.
  • 4Bjorck S,et al.Renal protective effect of enalapril in diabetic nephropathy.Br Med J,2009,304:339.
  • 5Maki DD,et al.Long-term effects of antihypertensive agents on proteinuria and renal function.Arch Intern med,2007,155:1073.
  • 6Wiliam F,Keane,Barry M,et al.The risk of developing end stage renal disease in patients with type 2 diabetes and nephropathy:the RENAAL study[J].Kidney Int,2003,63(4):1499-1506.
  • 7Nosadini R,Tonolo G.Role of oxidized low density lipoproteins and free fatty acids in the pathogenesis of glomerulopathy and tubulointersti-tial lesions in type 2 diabetes[J].Nutr Metab Cardiovasc Dis,2011,21(2):79-85.
  • 8World Health Organization. Definition, diagnosis and classifica- tion of diabetes mellitus. Report of a WHO consulation. Geneva: World Health Organization, 1999. 442 - 443.
  • 9宋·赵佶.圣济总录[M].北京:人民卫生出版社,2013.
  • 10国家食品药品监督管理局.中药新药临床指导原则[J].北京:中国科学技术出版社,2002:292-293.

引证文献5

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部