期刊文献+

835例慢性湿疹患者斑贴试验分析及临床意义 被引量:8

The analysis and the clinical significance of patch test on 835 cases of chronic eczema patients
原文传递
导出
摘要 目的:研究慢性湿疹患者斑贴试验的结果及临床意义。方法:对本科门诊确诊的835例慢性湿疹患者进行斑贴试验,并对结果作统计学处理。结果:斑贴试验总阳性率85.39%,性别、年龄差别无统计学意义,局限型皮损者阳性率看似高于泛发型,但无统计学意义。阳性率居前5位的变应原依次为:重铬酸钾、硫酸镍、卡巴混合物、甲醛和芳香混合物,其中卡巴混合物的阳性率男性明显高于女性,芳香混合物阳性率女性明显高于男性。41.55%的病例同时存在3种及以上的阳性变应原。结论:重铬酸钾、硫酸镍、卡巴混合物、甲醛和芳香混合物是本地区慢性湿疹的常见变应原,男女患者对卡巴混合物和芳香混合物的反应存在差异,斑贴试验对慢性湿疹寻找致敏原及日常防护具有重要意义。 Objective:Investigating the results of the patch test of chronic eczema patients and the clinical significance of the test results.Methods: Patch test on the 835 confirmed chronic urticaria patients and process the results statistically.Results: The rate of positive result in patch test is 85.39%,and it shows no difference between genders and ages.The positive rate is higher among the patients with localized skin lesions than that among the patients with generalized lesions,but it has no statistical significance in this test.The five allergens,which show the highest rate of positive result,in order are Potassium dichromate,Nickle sulfate,Carba mix,Formaldehyde and Fragrance mix,and among which,the rate of Carba mix positive of male is obviously higher than that of female and the rate of Fragrance mix positive of female is much higher than that of male.In 41.55% of these cases,the patients had three or more positive allergens.Conclusion: Potassium dichromate,Nickle sulfate,Carba mix,Formaldehyde and Fragrance mix are common allergens of chronic eczema in local region;the reactions to Carba mix and Fragrance mix of male and female are different;and the patch test on confirming the allergens and indicating the daily protection of chronic eczema is important.
出处 《中国卫生检验杂志》 CAS 2011年第1期103-105,共3页 Chinese Journal of Health Laboratory Technology
关键词 湿疹 斑贴试验 变应原 Eczema Patch test Allergens
作者简介 吴蓓玲(1964-),女,本科,副主任医师,主要从事中西医结合皮肤与性病学幅床方向研究。
  • 相关文献

参考文献10

二级参考文献24

  • 1王德旭,于秉伦,赵峰,苏东宝,张炜,刘康美.某些皮肤病接触性变应原的分析[J].中国麻风皮肤病杂志,2006,22(1):91-92. 被引量:5
  • 2谷永革,李军,于淑燕,冯憬,张理涛,张玉环.582例接触性皮炎、湿疹及荨麻疹患者斑贴试验结果分析[J].中国中西医结合皮肤性病学杂志,2006,5(1):40-41. 被引量:11
  • 3康莉,康定华,毕志刚.面部皮炎患者斑贴试验结果分析[J].中国美容医学,2006,15(12):1392-1393. 被引量:6
  • 4Pratt MD, Belsito DV, Deleo VA, et al. North American Contact Dermatitis Group patch-test results. 2001-2002 study period[J].Dermatitis,2004,15(4):176-183.
  • 5Jensen CS. Lisby S. Larsen JK. et al. Characterzation of lymphocyte subpopulations and eytokine profiles in peripheral blood of nickel-sensitive individuals with systemie contact dermatitis after oral nicel exposure[J].Contact Dermatitis,2004,50(1):31-38.
  • 6赵辨.临床皮肤性病学.3版.南京:江苏科技出版社,2006:604-606.
  • 7Wahlbeng JE. Diagnositic patch test. Rycroft RGJ. Testbook of contact dermatitis. Berlin: Springer-Verlag, 1992: 241.
  • 8张书岭 王瑛 冯曼君.湿疹接触性皮炎等皮肤病145例斑贴试验结果[J].中华皮肤科杂志,1998,31(4):255-255.
  • 9Wahlberg J E,Patch testing [A].In: Rycroft RJ G, Menne T, Frosch PJ (eds) . Textbook of contact dermatitis.2nd edition. Berlin:Springer 2 Verlag, 1995.241 - 265.
  • 10Bangha E, Elsner P. Sensitizations to allergens of the European standard series at the Department of Dermatology in Zurich 1990 - 1994. Dermatology, 1996, 193: 17-21.

共引文献488

同被引文献37

  • 1黄秀英,尹锐,钟白玉,黄云辉,宋志强.重庆地区470例皮炎湿疹类疾病患者斑贴试验结果分析[J].实用皮肤病学杂志,2009,2(4):206-207. 被引量:9
  • 2李林峰,刘广仁.职业性接触性皮炎的重要性及我国研究报告现状分析[J].中国工业医学杂志,2004,17(6):384-386. 被引量:19
  • 3王文静,薛咏梅,赵荣华,饶高雄.何首乌的化学成分和药理作用研究进展[J].云南中医学院学报,2007,30(3):60-64. 被引量:62
  • 4张学军,何春涤,陆洪光,等.皮肤性病学[M].7版.北京:人民卫生出版社,2009:139-141.
  • 5Wang Jiahua, Mao Wei, Wang Xiaohua, et al. Compound Glycyrrhizin Injection on eczema on cell immune function in patients with[J], modem Chinese physician, 2011, 28(22) : 561.
  • 6Zug KA, Warshaw EM, Fowler JF Jr, et al. Patch-test results of the North American Contact Dermatitis Group 2005- 2006. Dermatitis, 2009,20( 3 ) : 149-160.
  • 7Wetter DA, Yiannias JA, Prakash AV, et al. Results of patch test- ing to personal care product allergens in a standard series and a supplemental cosmetic series: an analysis of 945 patients from the Mayo Clinic Contact Dermatitis Group, 2000-2007[J]. J Am Acad Dermatol, 2010, 63:789-798.
  • 8Baltina LA. Chemical modification of glycyrrhizic acid as a route to new bioactive compounds for medicine [ J 1- Curr Med Chem, 2003,10 ( 2 ) : 155 -171.
  • 9Tasaka K. Epinastine : an update of its pharmacology, metabolism, clini- cal efficacy and tolerability in the treatment of allergic disease[J].Drugs Today (Barc) ,2000,36 ( 1 1) : 735-75.
  • 10Semsettin B, Sinan E, Nigar V. Comparison of the effects of topical cyclosporine 0. 05%, cyclosporine 2% , epinastine hydrochloride 0. 05%, and prednisolone acetate 1% on allergic in flammation in an experimental allergic conjunctivitis model [ J]. Cornea, 2013, 32 ( 11 ) :1465-1469.

引证文献8

二级引证文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部