摘要
多细胞生物在发生、发展过程中，为了保持正常的生理机能，一部分的细胞发生自发性细胞死亡，这种细胞死亡是被细胞内一系列相关的分子所调控，并伴随有典型的形态学改变，这种现象被称为细胞凋亡（ａｐｏｐｔｏｓｉｓ）［１］。作为一种积极排除生物体内的过剩细胞和有害...
Apoptosis,also termed programmed cell death,is a process whereby developmental or environmental stimuli activate a genetic program to implement a specific series of molecular mechanisms that culminate in the death and efficient disposal of a cell.In this papaer,the major distinctions between apoptosis and necrosis were described briefly.The pathways of intracellular signal transduction were presented in detail including inducing phase and enforcement phase of apoptosis.The intrinsic and extrinsic factors for inducing apoptosis were explained.Some important roles of p53,caspase,Bcl 2,ceramide etc in the apoptotic process were revealed,In the present paper there were 20 references quoted.
出处
《生物工程进展》
CSCD
1999年第3期40-44,共5页
Progress in Biotechnology
