摘要
对３４例经手术及病理证实的脑胶质瘤患者施行超选择性动脉灌注ＴＩＬ／ＩＬ－２，检测治疗前后ＣＴＬ毒性及ＣＤ４＋、ＣＤ８＋、ＣＤ４＋／ＣＤ８＋，结果均有显著性差异（Ｐ＜０．０５）。认为超选择性动脉灌注ＴＩＬ／ＩＬ－２能够使特异性ＣＴＬ毒性及Ｔ４、Ｔ８活性明显增强。
Thirtyfourpatientswithsurgicalandphathologicalprovenbraingliomasweretreatedbysuperselectiveintrarterialperfussionoftumorinfiltratinglymphocytes(TIL)andinterleukin2(IL2)TheCTLtoxicity,CD4+,CD8+andCD4+/CD8+ratioweredeterminedbeforeandaftertreatmentResults demonstrated that there were significant difference between the pretreatment and posttreatment levels of the CTLtoxicity,CD4+,CD8+andCD4+/CD8+ratio(P<005)Wecouldconcludethatthesuperselectiveintrarterialperfussionoftumorinvasivelymphocytes(TIL)andinterleukin2(IL2)wouldincreasethespecialCTLtoxicityandactiveofT4,T8cellsdominantlySoitcouldbeusedasanimportantsupplementaryofbraingliomapostopearitivetreatment
出处
《山东医药》
CAS
北大核心
1999年第10期15-16,共2页
Shandong Medical Journal
关键词
脑肿瘤
胶质瘤
动脉灌注
TIL
白细胞介素2
MalignantgliomaTumorinvasivelymphocyteInterleukin2CellimmuneIntrarterialsuperselectiveperfussion
