摘要
目的:观察奥曲肽联合凝血酶治疗老年上消化道出血的疗效。方法:对证实为上消化道出血的77例老年患者,随机分为奥曲肽组、凝血酶组及联合组,奥曲肽组采用首剂0.1mg静脉推注,再以(25～50)μg/h持续静脉泵入,凝血酶组采用凝血酶2000U加生理盐水15～20ml口服或胃管注入,每4～6h一次,联合组采用首剂0.1mg静脉推注,再以(25～50)μg/h持续静脉泵入,同时凝血酶2000U加生理盐水15～20ml口服或胃管注入,每4～6h一次。结果:联合组止血总有效率达92.3%,较奥曲肽组及凝血酶组明显增高,而其止血平均时间及症状改善平均时间则均较奥曲肽组及凝血酶组明显降低,差异具有统计学意义(P<0.05)。三组间不良反应无明显差别。结论:奥曲肽联合凝血酶治疗老年上消化道出血效果显著,具有良好疗效。
Objective：To observe the effects of treatment with octreotide and thrombin on patient with upper gastrointestinal bleeding. Methods：77 elder patients diagnosed as upper gastrointestinal bleeding from January 2008 to December 2009 were randomly divided into the combined treatment group,the oetreotide group and the thrombin groups.While the patients in combined treatment group were treated with octreotide and tllrombin,the patients in control group were treated with octreotide and thrombin only.Results：The effective rate in the combined treatment group was significantly increasingly compared with those in the control group. While the average hemostasis time and symptom improving time of the combined treatment group were reduced more significantly than those in the control group.Conclusion：The treatment with oetreotide and thrombin on patients with upper gastrointestinal bleeding is very effective.
出处
《中国医药导刊》
2010年第12期2084-2085,共2页
Chinese Journal of Medicinal Guide
关键词
奥曲肽
凝血酶
上消化道出血
Octreotide
Thrombin
Upper gastrointestinal bleeding
