摘要
报告1例儿童大疱性类天疱疮。患儿男,18个月。2个月前躯干和双下肢皮肤出现紧张性水疱、大疱,尼氏征阴性,外用糖皮质激素治疗效果不佳。皮损组织病理检查示表皮下水疱;直接免疫荧光示:IgG、C3沉积于基膜,间接免疫荧光示抗表皮基膜抗体阳性。诊断为儿童大疱性类天疱疮,予以口服泼尼松治疗后痊愈。
An 18-month-old bullous pemphigoid patient is reported. He developed a generalized blistering disorder 2 months ago. Histopathology revealed a subepidermal blister. Direct immunofluorescence showed linear depositions of IgG and C3 along the basement membrane zone. Indirect immunofluorescence studies demonstrated the presence of circulating immunoglobulin G antibodies directed a gainst the hemidesmosome. The patient was diagnosis as bullous pemphigoid. The patient was successfully treated by prednisone
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2011年第1期27-28,共2页
Journal of Clinical Dermatology
关键词
类天疱疮
大疱性
儿童
pemphigoid, bullous
childhood
作者简介
陈筱筱：现在金华市中心医院皮肤科工作．321000
