摘要
目的探索肾移植术后感染发生的规律。方法回顾分析我院808例次肾移植中各种感染的临床资料。结果808例次肾移植中发生各种感染180例次(20.7%),死亡35例(19.4%),其中应用硫唑嘌呤和泼尼松者的感染发生率及死亡率较使用以环孢素A为主的三联疗法者为高。已证实感染原的特异性感染69例次,特异性感染的病原最常见者为病毒。结论感染是肾移植后的常见并发症,正确调整免疫抑制剂剂量。
Objective To investigate the rule of infection occurrence
after renal transplantation. Methods Clinical data of various infections after renal
transplantation in 808 casetimes in our hospital were retrospectively analyzed. Results 180
casetimes infections (20.7%) occurred in 808 casetimes renal transplantations with the mortality
being 19.4%. The morbidity and mortality from infection were higher in recipients receiving
administration of the traditional immunosuppressive drugs than cyclosporine A. Lung infection
was the commonest and virus the most usual pathogen. Conclusion The infection was the
common complication after transplantation. Correct immunosuppressant dosage, etiologic
diagnosis in time and accurate application of antibiotic treatment were the keys of the treatment.
出处
《中华器官移植杂志》
CAS
CSCD
1999年第3期144-145,共2页
Chinese Journal of Organ Transplantation