期刊文献+

抑郁症患者体液免疫的变化及临床意义 被引量:3

原文传递
导出
摘要 目的 探讨抑郁症患者体液免疫功能的变化及临床意义.方法 采用免疫透射比浊法检测抑郁症患者89例及健康对照者40例的血清免疫球蛋白G(IgG)、免疫球蛋白A(IgA)、免疫球蛋白M(IgM)、补体3(C3)、补体4(C4)的水平.结果 (1)病例组IgG、IgA和IgM水平明显高于健康对照组(P<O.05),病例组C3水平明显低于健康对照组(P<0.05);(2)轻度、中度和重度抑郁组的体液免疫功能比较差异无统计学意义(P>O.05).结论 抑郁症患者存在体液免疫的功能紊乱.
出处 《中国医师杂志》 CAS 2010年第11期1546-1547,共2页 Journal of Chinese Physician
  • 相关文献

参考文献4

二级参考文献49

  • 1袁浩龙,戴永干,张莉,赵玉山,蔡剑虹.血清胆固醇水平与精神分裂症自杀未遂[J].临床精神医学杂志,1996,6(6):342-344. 被引量:7
  • 2Suvas S,Kumaraguru U,Pack CD,et al. CD4^+ CD25^+ Tcells regulate virus-specific primary and memoryCD8^+ Tcell responses[ J]. JExp Med ,2003,198 : 889-901.
  • 3Theodoropoulou S, Spanakos G, Baxevanis CN, et al. Cytokine serum levels, autologous mixed lymphocyte reaction and surface marker analysis in never medicated and chronically medicated schizophrenic patients [ J ]. Schizophr Res ,2001,47 : 13-25.
  • 4Maes M, Bosmans E, Ranjan R. Lower cc16, anatural anti-inflammatory protein and increased plasma interleukine I receptor antagonist in schizophrenia:effects of Antipsychotic drugs [ J ]. Schizophr Res,1996,21:39.
  • 5Besedovsky HO, del Rey A. Immuneneuroendocrine interactions facts and hypotheses [ J ]. Endocr Rev, 1996,17:64-107.
  • 6Maes M, Bosman E, DeJongh R, et al, Increased serum IL-6 and IL- 1 receptor antagonist concen trations in major de-pression and treatment resistant depression [ J ]. Cytokine [ J ]. 1997,9 : 853-858.
  • 7Sandrini M, Vitale G, Pini LA. Effect of rofecoxib on nociception and the serotonin system in the rat brain. Inflamm Res, 2002, 51 :154-159.
  • 8Bosetti F, Weerasinghe GR, Rosenberger TA, et al. Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. J Neurochem, 2003, 85:690-696.
  • 9Bosetti F, Rintala J, Seemann R, et al. Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E (2)concentration in rat brain. Mol Psychiatry, 2002, 7:845-850.
  • 10Kaufmann WE, Worley PF, Pegg J, et al. COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci USA, 1996, 93:2317-2321.

共引文献15

同被引文献21

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部