摘要
采用沉淀聚合法制备氯霉素分子印迹聚合物。以α-甲基丙烯酸(MAA)为功能单体,二甲基丙烯酸乙二醇酯(EDMA)为交联剂,氯霉素、MAA、EDMA摩尔比为1:4:20,以乙腈-水作为溶剂,偶氮二异丁腈(AIBN)作为引发剂,在60℃、400r·min-1条件下搅拌聚合,制备出的氯霉素印迹分子聚合物平均粒径为13.83μm,最大吸附量约为85μmol·g-1,远高于未加水制得的MIPs的最大吸附量9.49μmol·g-1。Scatchard分析得到一线性方程,说明制得的MIPs表面具有均一选择性的吸附位点,其最大表观吸附量为529.42μmol·g-1。
Precipitation polymerization was used to prepare molecular imprinted polymers（MIPs） of chloramphenicol.using chloramphenicol as template molecular,MAA as the functional monomer,ethylene glycol dimethacrylate as the cross-linker（chloramphenicol：MAA：ethylene glycol dimethacrylate was 1：4：20（mole ratio））,acetonitrilewater system as the porogenic solvent,and 2,2＇-Azobisiso butyronitrile as the initiator,chloramphenicol molecular imprinted polymer microspheres with an average size of 13.83 μm were synthesized with water bathing at 60 ℃ and stirring at the speed of 400 r·min-1.The product showed a maximum adsorption of 85 μmol·g-1 for chloramphenicol.Linear equation was obtained by Scatchard analysis,which illustrated that there were homogeneous selectivity adsorption sites on the surface of MIPs and its maximum apparent adsorption was 529.42 μmol·g-1.
出处
《四川大学学报（工程科学版）》
EI
CAS
CSCD
北大核心
2010年第6期172-175,共4页
Journal of Sichuan University (Engineering Science Edition)
关键词
分子印迹聚合物
沉淀聚合法
含水溶剂
氯霉素
吸附特性
molecularly imprinted polymer
precipitation polymerization
water-containing medium
chloramphenicol
adsorption characteristics
作者简介
作者简介：梁冰（1957-），男，教授．研究方向：分析化学．E—mail：liangbing@sina．com.
