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供血员、血液透析及非甲~庚型肝炎患者中TTV的感染状况 被引量:2

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摘要 目的:了解供血员、血液透析及非甲~庚型肝炎患者中输血传播病毒(TTV)的感染状况。方法:对40份供血员标本、27例血液透析及60例散发性非甲~庚型肝炎患者血清标本,采用PCR方法检测TTV-DNA,分析TTV的感染状况。结果:40份供血员血清中,有5例检出TTV—DNA阳性,检出率为12.5%;血液透析患者中TTV的检出率为22.2%(6/27),而60例散发性非甲~庚型肝炎患者血清中,无1例检出TTV-DNA。在11例TTV-DNA阳性的观察对象中,只有1例AlT轻度异常(58U/L)。结论:①广州地区存在TTV感染者。②输血具有传播TTV的风险,血液透析患者是TTV感染的高危人群。③TTV感染可能有一定的致病性,但其致病性强弱,有待进一步探讨。
出处 《临床荟萃》 CAS 1999年第10期435-436,共2页 Clinical Focus
基金 广东省自然科学基金资助
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参考文献1

二级参考文献3

  • 1谭德,J Hepatol,1995年,23卷,239页
  • 2团体著者,中华传染病杂志,1995年,13卷,3期,241页
  • 3高志良,中山医科大学学报,1994年,15卷,3期,69页

共引文献11

同被引文献30

  • 12,Leary TP,Muerhoff SA, Simons JN,et al.Sequ-ence and genomic organization of GBV-C: A novel member of the flaviviridae associated with human nonA-E hepatitis.J Med Virol,1996,48:
  • 23,Linnen J,Wages J, Zhang-Keck ZY,et al .Mo-leculer cloning and disease association of hep-atitis G virus:A transfusion-transmissible agent.Science,1996,27:505-508
  • 34,Nishizawa T, Okamoto H, Konishi K, et al. A novel DNA virus(TTV)associated with elevated transaminase levels in post-transfusion hepatitis of unknown etiology. Biochem Biophysi Res Commum,1997,241:92-97
  • 45,Simmond P, Davidson F,Lycett C, et al. Detec-tion of a novel DNA virus(TTV) in blood donors and blood products.Lancet,1998,352:191
  • 56,Greame WD,Gane E, Okamoto H.Hepatitis TT virus is present in New England. N Engl J Med, 1998,111(1066):195
  • 68,Okamoto H, Nishizawa T,Kato N, et al.Mole-cular cloning and characterization of a novel DNA virus(TTV) associated with posttransfu-sion hepatitis of unknown etiology. Hepatology Res,1998,10:1-16
  • 79,Alter HJ, Nakatsuji Y, Melpoler J, et al. The incidence of transfusion associated hepatitis G virus infection and its relation to liver disease.N Engl J Med,1997,336:747
  • 810,Alter HJ, Gallagher M, Morris TT,et al.Acute nonA-E hepatitis in the United State and therole of hepatitis G infection. N Engl J Med,1997,336:741
  • 912,Naoumov NV, Petrova E,Thomos MG, et al. Presence of a newly described human DNA virus (TTV) in patients with liver disease.Lancet,1998,352:195
  • 1013,Cossart Y. TTV a common virus. but patho-genic?Lancet,1998,352:164

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