摘要
采用苯胺和冰醋酸(乙酸酐)为原料,通过分馏法、回流法、干燥法、回流-干燥法、微波辐射法合成了乙酰苯胺.从绿色化学理念出发,进行反应方法探究和比较,优选出合理、实用、可行的制备方法.回流-干燥法和微波法是较佳的合成方法,不仅操作简便,反应时间缩短,而且提高了反应产率,使实验操作更加绿色化,也可为探究性实验的设计提供借鉴.
Acetanilide can be prepared from aniline in several ways,using glacial acetic acid or acetic anhydride as starting materials.The fractional distillation,reflux,dry distillation,reflux-dry distillation and microwave irradiation heat are present methods.From both green chemistry point of view and experimental procedure,the reflux-dry distillation is preferred for laboratory synthesis because their notable improvement in shorting time,improving yield and simplifying procedure.
出处
《甘肃高师学报》
2010年第5期16-18,共3页
Journal of Gansu Normal Colleges
基金
兰州城市学院绿色化学与环境保护重点学科建设项目
关键词
乙酰苯胺
回流-干燥法
微波辐射
绿色化学实验
acetanilide
reflux-dry distillation
microwave irradiation
green chemistry experiment
作者简介
作者简介：张力（1955-），男，山西平遥人，副教授．研究方向：绿色化学实验．
