摘要
人们在农业畜牧业和治疗人类疾病的过程中大量使用抗生素,由于抗生素自身独特的代谢特点,导致了抗生素在包括水体和土壤等环境介质中的残留,并因此导致对不同生物及生态系统产生广泛而深远的影响。本文概述了目前抗生素分子生态毒理学方面的研究进展,并阐述了抗生素对生物及生态系统的各分子水平的毒性机理及分子标记物研究情况,对于一些较新的分子诊断方法也进行了总结。最后,分析了抗生素分子生态毒理研究存在的不足,并探讨了今后的研究重点。
In recent decades,antibiotics have been widely used as the medicines for human and livestock. However,a large percentage of ingested antibiotics in living organisms are not metabolized but excreted and released as toxic contaminants,inducing their incremental residue in soil and aquatic environment,and resulting in adverse effects on living organisms and ecosystems. This paper summarized the research progress in molecular ecotoxicology of antibiotics,molecular mechanisms of antibiotics toxicity to living organisms and ecosystems,and ecotoxicological studies on molecular biomarkers of antibiotics,and summed up the new molecular diagnostic techniques applied in ecotoxicology. Some deficiencies of current molecular ecotoxicological diagnosis were pointed out,and the future study on the ecotoxicology of antibiotics was prospected.
出处
《生态学杂志》
CAS
CSCD
北大核心
2010年第10期2042-2048,共7页
Chinese Journal of Ecology
基金
国家自然科学基金资助项目(40930739和20977053)
作者简介
董璐玺，女，1985年生，硕士研究生，主要研究方向为污染生态毒理。E-mail：iamcivy@sohu.com
通讯作者E-mail：zhouqx@nankai.edu.cn
