摘要
目的:探讨血培养阳性脓毒症预后与转归的危险因素,进一步指导临床治疗。方法:对145例血培养阳性脓毒症的病历资料进行回顾性研究,使用SPSS13.0软件进行单因素分析以及Logistic回归分析,筛选可能的死亡危险因素。结果:单因素分析显示,经验选择抗生素是否符合药敏,功能障碍器官数目,基础疾病包括血液病、实体恶性肿瘤以及原发感染灶为肺部共5项指标与血培养阳性脓毒症预后与转归相关,使用Logistic回归进一步筛选出4个与血培养阳性脓毒症预后与转归相关的因素是:经验选择抗生素是否符合药敏,功能障碍器官数目以及基础疾病包括血液病、实体恶性肿瘤。结论:经验选择抗生素不符合药敏,两个和两个以上器官功能障碍以及基础疾病包括血液病、实体恶性肿瘤是血培养阳性脓毒症死亡的独立危险因素,应采取积极干预措施。
Objective To investigate the risk factors of prognosis and outcome in hemoculture positive sepsis in order to guide the clinical treatment further. Method The medical records data of 145 cases of hemocuhure positive sepsis were studied retrospectively,to screen out the potential risk factors with single - factor analysis and Logistic regression analysis by SPSS13.0. Results The results of single - factor analysis showed that 5 indicators were related to the prognosis and outcome in hemocuhure positive sepsis：whether the choice of antibiotics by experience was susceptibility, the number of organ with dysfunction,the underlying diseases including blood diseases and the solid cancer,as well as the primary infections found in hmg. The results of Logistic regression analysis further showed that 4 factors were related to the prognosis and outcome in hemocuhure positive sepsis ： whether the choice of antibiotics by experience was suseeptibility, the number of organ with dysfunction,the underlying diseases including blood diseases and the solid cancer. Conclusion There are 4 risk factors of death in he- moculture positive sepsis：the choice of antibiotics by experience not susceptibility, above 2 organs with dysfunction, the underlying diseases including blood diseases and the solid cancer, and the intervene measures should be taken actively.
出处
《吉林医学》
CAS
2010年第25期4240-4242,共3页
Jilin Medical Journal
