摘要
目的了解不孕女性生殖道解脲支原体(Uu)、人型支原体(Mh)和沙眼衣原体(Ct)感染状况并对支原体药敏进行分析。方法采用法国VEDA LAB公司的衣原体抗原检测卡,采用培养法检测支原体及其药物敏感试验。结果 416例样本中Uu阳性322例占77.4%,Mh阳性127例占30.5%,Ct阳性107例占25.7%;Uu对交沙霉素最敏感,敏感率为98.5%,其次为克拉霉素(98.0%)、强力霉素(96.5%);Uu+Mh对交沙霉素最敏感,敏感率为94.0%,其次为强力霉素(92.5%)、米诺霉素(74.6%);交沙霉素、克拉霉素、强力霉素、米诺霉素可做为本地区治疗支原体感染的一线抗菌药物。结论对不孕女性生殖道衣原体、支原体检测及药物敏感试验,可以针对性进行治疗,提高治愈率。
OBJECTIVE To investigate the status of ureaplasma urealyticum（Uu）,mycoplasmahominis（Mh） and chlamydia trachomatis（Ct） infection in genital tract of infertile female patients,and to analyze the drug sensitivity of mycoplasma.METHODS The mycoplasma was detected by using chlamydia antigen detection card（VEDA LAB） and its drug sensitivity was performed.RESULTS Among 416 cases of samples,there were 322 Uu,127 Mh and 107 Ct positive samples,accounting for 77.4%,30.5% and 25.7%,respectively.The results of drug sensitivity experiment showed that Uu was most sensitive to josamycin,with a high sensitive rate of 98.5%,secondly was clarithromycin（98.0%）,and thirdly was doxycycline（96.5%）.Uu＋Mh were most sensitive to josamycin,with the sensitive rate of（94.0%）,followed by doxycycline（92.5%） and minomycin（74.6%）.These indicated that josamycin,clarithromycin,doxycycline and minomycin could be used as effective antibiotics to treat mycoplasma infection in the area.CONCLUSION To conduct the detection of mycoplasma and chlamydia in genital tracts of infertile female patients and the drug susceptibility test can improve the cure rate of chlamydia and mycoplasma infection by targeted treatment.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第18期2884-2885,共2页
Chinese Journal of Nosocomiology
关键词
不孕女性
支原体
衣原体
药物敏感试验
Infertile female
Mycoplasma
Chlamydia
Drug sensitivity test
