摘要
各型病毒性肝炎及活动性肝硬化患者共213 例,采用镉柱还原法及重氮化法检测NO-2 /NO-3 水平,放免法检测ET- 1 水平。急性肝炎、慢性活动型肝炎、肝炎肝硬化等各型肝病患者血清NO-2 /NO-3 及ET- 1 水平均有不同程度的升高,肝炎急性期NO 就有明显升高,慢性肝病NO与ET随病情进展水平升高。
To study the alterations and significance of the plasmalevers of nitric oxide(NO) and endothelia(ET) in patients with viralhepatitisandlivercirrhosis-Plasmaleversof NO-2 /NO-3 and ET 1 were measured using Griessreaction and IFAin 213 cases of patients with viral hepatitisincluded acute icteric hepatitis,acute non icteric hepatitis,chronic persistent hepatits,chronic active hepatitis and liver cirrhosis-The plasmalevers of NO-2 /NO-3 were allelevated( P< 0-01)exceptforthe group of chronic persistenthepatitis-The plasma levels of ET 1 were elevated in groups of acute icteric hepatitis( P< 0-05) ,chronic active hepatitis and liver cirrhosis( P< 0-01)-And there were positive correlation be tween thelevels of NO-2 /NO-3 and ET 1-
出处
《临床肝胆病杂志》
CAS
北大核心
1999年第2期93-95,共3页
Journal of Clinical Hepatology
关键词
病毒性肝炎
肝硬化
一氧化氮
内皮素
Viral hepatitis Liver cirrhosis Nitric oxide Endothelin