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血清TGAb和TPOAb在桥本甲状腺炎诊断中的意义 被引量:16

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摘要 目的探讨甲状腺球蛋白抗体(TG-Ab)和甲状腺过氧化物酶抗体(TPO-Ab)在桥本甲状腺炎诊断中的意义。方法电发光免疫分析法分别检测桥本甲状腺炎甲状腺功能正常223例和231例甲状腺功能低下患者血清中TG-Ab和TPO-Ab的含量。结果桥本甲状腺炎组(包括甲状腺功能低下和甲状腺功能正常者)TG-Ab和TPO-Ab的水平明显高于健康对照组(P<0.001),女性患者高于男性患者(P<0.05)。结论 TGAb和TPOAb两种抗体联合检测对与诊断桥本甲状腺炎和判断预后有重要意义。
出处 《临床和实验医学杂志》 2010年第17期1311-1312,共2页 Journal of Clinical and Experimental Medicine
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  • 1张中书,许瑞吉,王国洪.Graves’病患者的TPOAb及TRAb的变化与临床价值[J].放射免疫学杂志,2006,19(5):361-362. 被引量:6
  • 2Konno Y, Hiyama Y, Shimojo N, et al. Autoantibodies to thyroidperoxidase in patients with chronic thyroiditis: effect of antibody binding on enzyme activities. Clin Exp Immunol. 1986,65:534.
  • 3Feldt-Rasmussen U. Analytical and clinical performance goals for testing autoantibodies to thyroperoxidase, thyroglobulin and thyrotropin receptor. Clin Chem. 1996,42(1):160.
  • 4Vanderpump MPJ, Tunbridge WMG, French JM, et al. The incidence of thyroid disorders in the community : A twenty - years follow - up of the Whickham survey. Clin Endocrinol(Oxf). 1995,43:55.
  • 5Marino M,Chiovato L,Friedlander J A,et al.Serum Antibodies against megalin(GP330) in patients with autoimmune thyroiditis[].The Journal of Clinical Endocrinology.1999
  • 6AjjanRA,WeetmanAP.Pathogenesisofautoimmunethy roiddisease[]..1999
  • 7Li L,Paul S,Tyutyulkova S,et al.Catalytic activity of antithyroglobulin antibodies[].J Immunol.1995
  • 8Endo T,Kogai T,Nakazato M,et al.Autoantibody against Na+ /I- symporter in the sera of patients with autoimmune thyroid disease[].Biochemical and Biophysical Research Communications.1996
  • 9Gunji K,Bellis A,Li A Y,et al.Cloning and characterization of the novel thyroid and eye muscle shared protein G2s: autoantibodies against G2s are closely associated with ophthalmopathy in patients with Graves′hyperthyroidism[].The Journal of Clinical Endocrinology.2000
  • 10Knobel M,Umezawa E S,Cardia M S,et al.Elevated antigalactosyl antibody titer in endemic goiter[].Thyroid.1999

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