摘要
目的观察血清TBA、CHE、PA水平在各组肝病中的表现,了解其在肝病中的临床意义。方法测定急性肝炎、慢性迁延性肝炎、慢性活动性肝炎、肝硬化共4组263例肝脏疾病及50例健康对照组的血清TBA(酶循环法)、CHE(酶连续监测法)及PA(免疫透射比浊法)的水平,进行统计学处理。结果肝病各组与健康对照组比较三项指标差异均有统计学意义。三项指标在慢性迁延性肝炎中变化的幅度最小;而在其它肝病中,TBA均增高非常显著,CHE、PA则降低非常显著,尤其在肝硬化患者中最为显著。结论血清TBA、CHE、PA三项联合检测对肝脏疾病的诊断、鉴别诊断、治疗、病情发展及预后判断有十分重要的临床意义。
Objective To observe the performances of serum levels of total bile acid（TBA）,cholinesterase（CHE）and prealbumin（PA）in each group of liver disorder,and to know their clinical values.Methods The serum levels of TBA,CHE,and PA were determined in 263 patients with liver disorder,which were divided into 4 groups（acute hepatitis group,chronic persistent hepatitis group,chronic active hepatitis group,and hepatic cirrhosis group）,and 50 healthy controls.The determination results of the five groups were statistically analyzed.Results There were statistically significant differences in the serum levels of TBA,CHE,and PA between the control group and each liver disorder group.The change range of serum TBA,CHE,and PA levels in chronic persistent hepatitis group was the smallest.The serum level of TBA was significantly increased,but serum CHE and PA levels were significantly decreased in the other three groups of liver disorder,especially in hepatic cirrhosis group.Conclusions It is of great clinical value to jointly detect serum TBA,CHE and PA in diagnosis,differential diagnosis,treatment,disease development,and prognosis judgment of liver disorder.
出处
《实用预防医学》
CAS
2010年第8期1652-1653,共2页
Practical Preventive Medicine
关键词
总胆汁酸
胆碱脂酶
前清蛋白
肝病
Total bile acid
Cholinesterase
Prealbumin
Hepatopathy
作者简介
吴慧平（1972-），女，侗族，湖南省新晃县人，本科学历，主管检验师，主要从事临床检验工作。
