摘要
探讨反复呼吸道感染（RRYI）患儿血清β-胡萝卜素（β-CT）、维生素A（VA）、维生素E（VE）与免疫功能关系。方法采用高效液相色谱Miller改良法测定RRTI患儿血清β-CT、VA、VE含量，散射比浊法测定IgA、IgG、IgM，用McAb－ApAAp法测定外周血T淋巴细胞亚群，并与健康儿童对比。结果RRTI血清β-CT、VA含量明显低于对照组（P＜0．001）；RRTI血清IgA水平与β-CT、VA含量是显著正相关（r=0．347～0．441P<0．05）；RRTI组外周血CD+3；降低，CD+8增多，CD+4／CD+8比值降低，与对照组相比有显著差异性（P<0．001）。结论β-CT、VA缺乏时体液免疫和细胞免疫功能均降低，β-CT、VA缺乏可能是导致RRTI的重要原因。
To study the relationship between seurm β-carotene (β-CT). vitamin A (VA). vitamin E (VE)and immunologic function in children with recurrent respiratory tract infection (RRTI).Methods: Seurm β-CT, VA .VE with high pressure liquid chromatography(miller) and IgA. IgG. IgM with nephelometry and peripheral subtypes of T lymphocytes with alkaline phosphatese monoclonal antibody were carried out in RRTI children. The control group was taken simultaneously.Results: The seurm β-CT.VA in RRTI group were much less than that in control group (P<0. 001 );Seurm IgA had positive correlation with β-CT. VA in RRTI group (r = 0. 347 ～ 0. 441 P<0. 005 ); The peripheral CD+3. CD+4/CD+8 decreased and CD+8 increased in RRTI group. The two groups had much difference (P<0. 001 ).Conclusion: The humoral and celluar immunonities would decrease with the deficiency of β-CT and VA. These deficiency could lead to RRTI.
出处
《实用儿科临床杂志》
CAS
CSCD
1999年第1期7-8,共2页
Journal of Applied Clinical Pediatrics
关键词
呼吸道感染
血清
Β-胡萝卜素
VA
免疫功能
VE
recurrent respiratory tract infection (RRTI)
carotene (β-CT)
vitamin A (VA ).
