摘要
目的探讨原发性中枢神经系统淋巴瘤的早期诊断方法及综合治疗疗效观察。方法埘经病理及免疫组化证实的9例原发性中枢神经系统淋巴瘤患者均行放化疗治疗。结果经综合治疗后CR5例，PR2例，NC1例，PD1例。9例均得到有效随访，1例生存5个月后死亡；1例18个月后肿瘤复发。本组9例存活时间最短5个月，最长5年3个月，平均生存时间38个月。3年总存活率为78％，5年生存率44％。结论对病理诊断明确的PCNSL患者，进行以放疗为主、辅以全身静脉化疗的综合治疗，可以明显改善临床症状、延长生存期，提高生活质量。
Objective To investigate the early diagnosis and comprehensive observation on therapeutic effect of primary central nervous system lymphoma. Methods All the 9 patients with primary central nervous system lymphoma diagnosed by pathology and immunohistochemistry were received radiotherapy and chemothera- py. Results The Completed release was found in 5 patients,partial response in 2 patients, stable disease in 1 patient and progressive disease in 1 patient. All the 9 patients in the group were followed up sufficiently. One patient died after five months, and tumor recurrence in one patient after eighteen months. The shortest survival time of the 9 patients in the group was five months,the longest was five years and three months, and the average survival time was 38 months. 3-year survival rate was 78% , and 5-year survival rate was 44%. Conclusion The treatment of radiotherapy with assisted chemotherapy for patients with primary central nervous system lymphoma diagnosed by pathology could improve clinical symptoms, prolong survival time and improve life quality.
出处
《中国临床实用医学》
2010年第7期37-39,共3页
China Clinical Practical Medicine
关键词
中枢神经系统淋巴瘤
放疗
化疗
Primary central nervous system lymphoma
Radiotherapy
Chemotherapy
