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丹参酮ⅡA磺酸钠治疗冠心病心绞痛临床观察 被引量:9

Clinical Observation of the Effects of Sulfotanshinone Sodium on Angina Pectoris in Patients with Coronary Heart Disease
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摘要 目的观察丹参酮ⅡA磺酸钠对冠心病心绞痛的临床疗效。方法63例冠心病心绞痛的病人,随机分为两组,对照组27例,只用常规抗心绞痛药物治疗。治疗组36例,在常规抗心绞痛药物治疗基础上加用丹参酮ⅡA磺酸钠,观察两组的疗效,比较其有效率。结果治疗组36例,显效18例(50.0%),有效14例(38.9%),总有效率88.9%。对照组27例,显效12例(44.4%),有效8例(29.6%),总有效率74.0%,治疗组总有效率明显优于对照组(P<0.05)。治疗组全血高切粘度、低切粘度、红细胞聚集指数、血小板粘附率等均有明显改变。结论丹参酮ⅡA磺酸钠对冠心病心绞痛的治疗效果明显。 Objective To investigate the clinical effects of Sulfotanshinone Sodium on angina pectoris in patients with coronary heart disease.Methods 63 cases of coronary heart disease angina pectoris patients were randomly divided into experimental group and control group.The control group(n=27) cases were treated with the conventional anti-angina pectoris pharmacopoeia,and the experimental group(n=36) were treated with the conventional anti-angina pectoris pharmacopoeia combined with sulfotan-shinone sodium.Then,we observed two groups' clinical effects,and compared its effectiveness.Results Among the 36 cases in experimental group,19 cases had remarkable effects(50.0%),13 cases showed effectiveness(40.6%) and the total effectiveness was 90.6%.Among the 27 cases in control group,12 cases had remarkable effects(44.4%),8 cases showed effectiveness(29.6%),and the total effectiveness was 74.0%.The experimental group's total effectiveness surpassed that of control group.Conclusions Sulfotanshinone Sodium is obviously effective to coronary heart disease angina pectoris.
作者 胡杰
出处 《辽宁医学院学报》 CAS 2010年第3期216-218,共3页 Journal of Liaoning Medical University (LNMU) Bimonthly
关键词 丹参酮ⅡA磺酸钠 心绞痛 临床疗效 Sulfotanshinone Sodium angina pectoris clinical effect
作者简介 胡杰(1971),男,安徽省阜阳市人,主治医师,学士学位,主要研究方向为临床内科。
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参考文献3

  • 1李学文.心血管疾病[M].北京:科学技术文献出版社,1999.326-335.
  • 2Attele AS,Wu JA,Yuan CS.Ginseng pharmacology:multiple constituents and multiple actions[J].Biochem Pharmacol,1999,58(11):1685-1693.
  • 3袁成刚,范力,杨兵.丹参的临床应用进展[J].辽宁医学院学报,2009,30(4):366-368. 被引量:20

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