摘要
目的:探讨低剂量考来烯胺在甲状腺功能亢进(Hyperthyroidism,HT)患者术前准备中的作用。方法:67例HT患者被纳入此研究,随机、双盲分为2组,A组即考来西胺(2g,bid)的基础上联用硫脲类药物,B组2为常规硫脲类药物加Logul液。治疗4周后,检测患者血清甲状腺激素(TH)水平及基础代谢率(Basic metabolic rate,BMR),并进行统计学分析。结果:A组患者血清游离三碘甲状腺原氨酸(FT3)、游离甲状腺激素(FT4)、促甲状腺激素(TSH),以及BMR明显低于B2。结论:低剂量考来烯胺是一种有效,具有较好剂量耐受性的用于HT术前准备的药物。
Objective：To investigate the effect of lowdose of cholestyramine in the preoperotive preparation in hyperthroidism（HT）.Methods：Sixty-seven patients with HT were randomly and double blindedly divided into group A and group B,the former were give low dose of cholestyramine and thioureas,the latter were given tapazole（MMI）and Logul＇s liquid.Four weeks later,the level of TH and basic metabolism rate（BMR）were comparised between two groups.Results：The level of FT3,FT4,BMR,and the preoperotive preparation time were significantly priorier than those of group B（P〈0.05）,but there was no significant difference of TSH between two groups（P〉0.05）.Conclusion：It suggests that lowdose of（cholestyramine is beneficial for the preoperotive preparation in HT.
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2010年第5期784-785,共2页
Journal of Chongqing Medical University
关键词
考来西安
甲状腺功能亢进
术前准备
Cholestyramine
Hyperthroidism
Preoperotive preparation
作者简介
梁栋（1973-），男，主治医师，研究方向：普通外科。
