踝肱指数与2型糖尿病发生周围血管病变的相关性分析被引量：4

Correlative Analysis on Peripheral Artery Disease to the Ankle Brachial Index in Type 2 Diabetes

在线阅读下载PDF

导出

摘要目的:探讨踝肱指数(ABI)与2型糖尿病发生周围血管病变的相关性。方法:采用多普勒流速仪对174例2型糖尿病的踝肱指数进行测定,根据是否伴有周围血管病变分为2组,比较踝肱指数的差异;根据周围血管病变程度分为轻度和重度两组,比较其踝肱指数的差异。结果:174例2型糖尿病有周围血管病变16例,发生率9.20%。无周围血管病变的2型糖尿病的踝肱指数为0.98±0.14,明显高于有周围血管病变的2型糖尿病的踝肱指数0.76±0.13,p<0.05;重度周围血管病变的2型糖尿病的踝肱指数为0.32±0.16,明显低于轻度周围血管病变的2型糖尿病的踝肱指数0.82±0.15,p<0.05。结论:踝肱指数与2型糖尿病大血管病变发生密切相关,是2型糖尿病发生周围血管病变的有效初筛指标。 Objective：To analyze the correlation of peripheral artery disease to the ankle brachial index （ABI） in type 2 diabetes. Methods：174 cases with type 2 diabetes were divided into two groups according to accompanying with peripheral angiopathy,their ABI were evaluated and compared; 16 patients with peripheral angiopathy were divided into two groups according to the degree of vascular lesion,their ABI were evaluated and compared. Results：The incidence of peripheral angiopathy in type 2 diabetes was 9.20% （16/174）. The ABI of type 2 diabetes without peripheral angiopathy was 0.98±0.14,and higher than that of the type 2 diabetes with peripheral angiopathy; The ABI of type 2 diabetes with serious peripheral angiopathy was 0.32±0.16,and lower than that of the type 2 diabetes with general peripheral angiopathy. Conclusion：ABI is closely correlated with peripheral artery disease in type 2 diabetes. It is an effective predictor for peripheral arterial occlusion disease in type 2 diabetes.

作者吴雪艳左致煌王琼莲欧阳淑一李秀明王静姜佩佩郑立

机构地区广元市中心医院内分泌科

出处《川北医学院学报》 CAS 2010年第3期233-234,共2页 Journal of North Sichuan Medical College

关键词踝肱指数 2型糖尿病周围血管病变相关性 Ankle brachial index Type 2 diabetes Peripheral artery disease Correlation

分类号 R587.1 [医药卫生—内分泌]

作者简介吴雪艳（1973-），女，四川广元人，副主任医师，主要从事内分泌疾病的临床治疗与研究。E-mail：wxy19730123@163．com

引文网络
相关文献

参考文献5

1Norman PE,Davis WA,Bruce DG,et al.Peripheral arterial dis-ease and risk of cardiac death in type 2 diabetes:the Fremantle di-abetes study[J].Diabetes Care,2006,29(3):575-580.
2Oshimasa A,Ki-ichi O,Teruo I,et al.Results of blood inflam-matory maker are associate more strongly with toe-branhial index than with ankle-brachial index inpatients with type 2 diabetes[J].Diabetes Care,2004,27(7):1381-1386.
3Wild SH,Byrne CD,Smith FB,et al.Low ankle-brachial pres-sure index predicts increased risk of cardiovascular disease inde-pendent of the metabolic syndrome and conventional cardiovascular risk factors in the Edinburgh artery study[J].Diabetes Care,2006,29(3):637-642.
4中华医学会糖尿病学分会.中国2型糖尿病防治指南[M].北京:人民卫生出版社,2007.
5薛梅,石福彦.踝肱指数在糖尿病大血管病变中的应用[J].内蒙古医学杂志,2007,39(5):581-583. 被引量：6

二级参考文献16

1胡大一,王领军,余金明,布艾加尔,仝其广,王锦纹,魏毅东,吴琛.踝臂指数评价高危患者下肢外周动脉病多中心临床研究[J].中国医刊,2005,40(1):36-38. 被引量：54
2陈丽.运动后踝臂指数评价糖尿病下肢动脉病变[J].中国临床康复,2005,9(19):16-16. 被引量：2
3王昆,胡大一,杨进刚,李田昌,韩雅蕾,逯春鹏.踝臂指数与冠状动脉病变严重程度的相关性分析[J].临床荟萃,2005,20(24):1393-1395. 被引量：17
4PremalathaG,RavikumarR,SanjayR,et al.Com-parison of colour duplex ultrasound and ankle brachial pressure index measurements in peripheral vascular disease in type 2 diabetic patients with foot infections[J].Assoc Physicians India,2002,50:1240.
5Thomas A,Pearson MD.New Tools for Coronary Risk Assessment What Are Their Advantages and Limitations[J].Circulation,2002,105:886.
6CriqniMH,DenenbergJO,LangerRD,et al.The epidemiology of peripheral arterial disease:importance of identifying the population at risk[J].Vasc Med,1997,2(3):221.
7Paul E Norman,John W Eikelboom,Graeme J Hankey.Peripheral arterial disease prognostic significance and prevention of atherothrombotic complications[J].Clinical Update,2004,181(3):150.
8LaingP.The development and complications of dia-betic foot ulcers,[J].Am J Sung,1998,176(2A):11.
9SuzukiE,KashiwagiA,NishioY,et al.Increased Arterial Wall Stiffness Limits Flow Volume in the Lower Extremities in Type 2 Diabetic Patients[J].Diabetes Care,2001,24:2107.
10McDerm ottMM,MehtaS,GrennlandP.Exertional leg symptoms otb-er than intermittent claudication are common in peripheral arterial dis-ease[J].Arch Intern Med,1999.159:387.