摘要
目的观察小剂量氟哌利多合并芬太尼对七氟醚复合瑞芬太尼麻醉后苏醒期躁动的影响。方法选择80例乳腺癌改良根治手术的患者,术中用七氟醚吸入复合瑞芬太尼麻醉.随机分为A、B、C、D 4组,分别为氟哌利多+芬太尼组、氟哌利多组、对照组和芬太尼组,每组20例。观察不良反应、自主呼吸恢复时间、拔管时间、苏醒期躁动的发生率、躁动评分。结果未发现明显不良反应,各组自主呼吸恢复时间差异无统计学意义(P>0.05),A组拔管时间(8.3±1.7)min较C组(6.7±1.7)min增加,差异有统计学意义(P<0.05),但躁动评分和苏醒期躁动发生率(15%)都较C组降低,差异有统计学意义(P<0.05)。结论小剂量氟哌利多合并芬太尼预防七氟复合瑞芬太尼醚麻醉后苏醒期躁动是安全有效的。
Objective To investigate low-dose droperidol and fentanyl on the restlessness during the stage of analepsia after general anesthesia with sevoflurane combined with remifentanil.Methods Eighty class ASA Ior Ⅱ patiens undergoing elective modified radical mastectomy were randomly divided into A、B、C and D group with 20 cases each.The patients in group A were injected droperidol 2.5mg and fentanyl 0.1ug/Kg,and those in group B were only injected with droperidol,while the patients in group D were given fentanyl 0.1ug/Kg.The group C is the control group.Spontaneous breathing recovery time,extubation time,RS and adverse were recorded.Results Few side effects were observed.Extubation time was significantly prolonged in group A（8.3±1.7min）than in group C（6.7±1.7min）,while the lever of RS（0.15±0.37） and the incidence rate of restlessness（15%）were significntly lower in group A compared with those in group C.Conclusion Low-dose droperidol combined with fentanyl can safely and perfectly prevente the restlessness during emergency after sevoflurane-remifentanil based general anesthesia.
出处
《重庆医学》
CAS
CSCD
北大核心
2010年第11期1411-1412,共2页
Chongqing medicine
作者简介
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