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2-取代-3-氨基-4(3H)-喹唑啉酮类化合物的合成与表征 被引量：2

Synthesis and characterization of 2-substituted-3-amino-4(3H)-quinazolinones
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摘要 以(未)取代邻氨基苯甲酸与乙酐或芳甲酰氯反应并环化,生成2-甲基-4(H)-3,1-苯并噁嗪酮衍生物,该中间体与80%水合肼反应即得目标化合物,收率76.1%～90.1%。 （Un）substituted o-amino benzoic acids reacted with acetic anhydride,or aryl chloride by cyclization reaction to prepare the intermediates-2-methyl（or aryl）-4（3H）-3,1-benzoxazinone derivatives.The intermediates reacted upon 80% hydrazine hydrate to synthesize target compounds,4（3H）-quinazolinones,with the yield reaching 76.1%～90.1%.
作者 高兴文 严敏 刘玉琦 田烨
机构地区 贵州民族学院化学与环境科学学院
出处 《化学试剂》 CAS CSCD 北大核心 2010年第5期461-464,共4页 Chemical Reagents
基金 贵州省自然科学基金资助项目(2008-2230)
关键词 3-氨基-4(3H)-喹唑啉酮 4(H)-3 1-苯并噁嗪酮 邻氨基苯甲酸 合成 3-amino-4（3H）-quinazolinones 4（3H）-3 1-benzoxazinones anthranilic acid synthesis
分类号 O621.3 [理学—有机化学]
作者简介 高兴文（1956-），男，河南焦作人，博士，副研究员，主要从事有机合成研究。
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参考文献23

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共引文献26

同被引文献25

  • 1张陈,陆涛.2-取代-4(3H)-喹唑啉酮类化合物合成研究进展[J].精细化工中间体,2006,36(5):12-15. 被引量：5
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化学试剂
2010年 第5期

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